Ok as the plot for season 14 is known. Defeating the Alternate Michael inside of Dean. (Which I feel they added this Michael while leaving the one in hell. Was to save face as the actor that play Adam, normally never showed any interest in return) What could some new plots be for future seasons. I’ll list mine below.
1. A child of Amara: Crazy a bit but Amara could have had some kind of child with Dean when she was released from her prison. It wouldn’t have to been like, with Lucifer and Kelly making Jack. It could have been done simply from their first meeting. And her desire to replace him with God, might have produced a creation with the link they shared with the Mark as Dean had it last.
2. Leftover creations of God’s earlier worlds: As we know God created worlds before the current one. Maybe leftover creatures were saved but imprisoned them to later be released.
3. Natural Order. Not so much another Primordial Being. But maybe the Natural Order sends agents to kill Dean and Sam. After all they break the Universe’s Laws daily. Even Amara and God, and even Death and the Cosmic Entity follow it to some degree. Or breaking the Natural Order causes so many problems, these violations of the Natural Order caused like “universe cancer” that can’t be destroyed unless the ones that caused the violations die or fix the damage they have done.
4. The Shedim. Maybe the Shedim will be shown as demonic creatures so vile, that they attack and destroy even other Demons.
5. Hell like Heaven. Maybe Hell will have a similar function like Heaven with the Angels. To where Demons keep Hell going.