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Dick Roman Enhanced Regeneration

Dick Roman quickly regenerates after being doused in Borax.

Regeneration, also called Healing Factor, is the ability to heal wounds and injuries beyond that of a normal person. This ability does not however make its holder immortal or invulnerable, just more difficult to kill than normal beings.

Characters with this ability[]

  • The Darkness - Upon being wounded by a massive angelic smite, she regenerated by absorbing an angel's grace. Upon wounding God fatally, she regenerated instantly from many extensive wounds of her own, this time without any external help.
  • Archangels - Archangels are ancient primordial beings that possesses healing factors similar to, if not beyond the likes of regular Angels or Seraphim. Archangels can instantly heal from nearly completely any kind of physical damage weather it be conventional or supernatural means, there are only a very few things in existence they can't heal from.
    • Michael - When hit with holy fire, Michael was able to quickly regenerate from the damage and return to Stull Cemetery in only a few minutes.
    • Lucifer - Was able to heal from being shot with a hundred rounds of angel-killing bullets instantly, as well as being able to instantly heal from a shot through the head from the Colt.
    • Gabriel - Despite years of captivity and torture under Asmodeus, Gabriel was able to instantly heal himself when Asmodeus started threatening him.
  • Celestial Beings - When and if they can somehow receive damage, they will instantly heal the injury. If they are weak and the damage is severe, it may take much longer though their presence will keep their vessel alive.
    • Castiel - Castiel generally heals quickly as an angel, healing instantly from most of the injuries he has as long as they aren't severe. However, when Rachel injures him with an angel blade, Castiel is left weakened and takes some time to heal, needing to channel energy from Bobby Singer's soul just to bring Sam and Dean back from the past. It also took him some time to heal from a bullet made from an angel blade, a wound that was exacerbated by Crowley digging around in it.
    • Gadreel - Was so weakened by the Fall that he took months to heal, but while possessing Sam Winchester, was able to slowly heal both as long as he wasn't forced to use his powers. Once he regained his full strength, he was able to heal much faster but couldn't heal a wound from the First Blade.
  • Nephilim
    • Jack - The nephilim Jack, was able to instantly heal from a stab wound to the heart inflicted by an angel blade.
  • Demons - Many demons seem to possess this ability though when they leave their vessel, the injuries tend to return.
    • Lilith - She healed her vessel from being stabbed by antlers and from being shot in the head with a devil's trap bullet.
    • Alastair - Alastair was able to regenerate the wound after Sam stabbed him with the demon-killing knife.
    • Cain - As the first Knight of Hell, his healing factor is beyond the likes of a high-ranking demon. He can instantly heal from damages caused by the Demon Killing Knife. However, his limb regeneration was not seen completely, as he was killed before the regeneration process was complete, though he did manage to regenerate most of it.
    • Meg - Meg was shown to heal injuries from a fall and gunshot wounds but they returned when she left her vessel.
    • Ruby - Ruby healed a gunshot wound, as well as cuts she inflicted on herself to give her blood to Sam, and kept her vessel from decaying.
    • Crowley - Crowley was able to heal the various injuries he got over the series including gunshot wounds and damage from Photokinesis. However, unlike other demons, the injuries did not seem to reappear when he left his vessel.
    • Dean Winchester (formerly) - After being transformed into a Knight of Hell, the wound that killed Dean healed as did any other injury he received near-instantly.
  • Eve - It is assumed since she is at least part Leviathan, she can regenerate any injuries she does receive.
  • Leviathans - Leviathans can heal from any mortal or fatal injury inflicted by natural or supernatural means alike, except for the The Bone of Righteous Mortal Washed in Three Bloods of The Fallen.
    • Dick Roman - Their head, Dick can heal from injuries at an even faster rate than his subordinates.
    • Edgar - A high-ranking Leviathan, Edgar regenerated moments after being smashed by a falling vehicle, and appearing unharmed by the ordeal.
  • Nachzehrer - Have limited regeneration, if their head it missing, it needs to be reattached manually.
  • Okami - Okami can regenerate any non-fatal wounds, one fully regenerated after being stabbed with a bamboo dagger.
  • Phoenix - Can regenerate any non-fatal wound.
  • Prometheus - Following his resurrections any wounds would instantly heal.
  • Shapeshifter - Able to heal any wound non-lethal to them.
  • Skinwalker - Able to heal from a bullet wound, and being hit by a car.
  • Vampires - Also able to heal any non-lethal wounds. Process accelerated by drinking blood.
  • Witches - Extremely powerful witches can access this ability via Magic.
  • Werewolves - Able to heal anything non-lethal to them. Purebloods can even heal their original bites. One werewolf was able to heal fatal injuries from a car accident she received while human.
  • Wraith - Wraiths can regenerate their spikes if they are broken off.
  • Zombies - Actual and Croaton Zombies can regenerate wounds.
    • Angela Mason - Has very potent healing abilities and will always regenerate, as long as the weapon used to wound her was not silver. 
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