| “ | I'm stronger than that now. Now I can kill. | ” |
| “ | I've killed innocent people in the line of duty. But I'm pretty sure it's not something the old me could've done. And maybe I should feel guilty. But I don't. | ” |
Beings killed by Sam Winchester.
Angels[]
Higher Angels[]
- Alternate timeline Zachariah - Stabbed in the heart with an angel blade.
Regular Angels[]
- One of Arthur and Charlie's Captors - Stabbed in the chest with an angel blade.
- Miriam - Stabbed through the heart with an angel blade.
Demons[]
Princes of Hell[]
- Ramiel - Stabbed in the heart with the Lance of Michael, causing him to explode into dust.
Crossroad Demons[]
- Dar (presumably) - Presumably killed after torturing her for information on Dean's whereabouts.
- Dean's Crossroad Demon - Shot in the head with the Colt when she wouldn't break Dean's deal.
- Robin's captor - Killed during Sam's soulless period.
- Unnamed Crossroad Demon - Killed with the demon-killing knife after he wouldn't trade Sam's soul for Dean's.
White-eyed demons[]
- Alastair - Tortured and killed with his powers as one of the Special Children.
- Lilith - Killed with his powers as one of the Special Children. Required all of the demon blood from one demon and more from another.
Regular Demons[]
- Blood Source Demons - Throats slit by Sam with the demon-killing knife in order to collect all of their blood.
- Brady - Stabbed in the stomach with the demon-killing knife.
- Bunker Incursion Demons - Stabbed one with an angel blade. Killed three others alongside Castiel and Gabriel.
- Carl's demon - Stabbed in the chest with the demon-killing knife.
- Casey - Shot with the Colt.
- Cindy McKellan's demon - Alongside Ruby, drained of blood to power his abilities.
- Four Iowa Factory Guards - Vaporized with a demon bomb.
- Four Nebraska Factory Guards - Two stabbed with an angel blade and two vaporized with a demon bomb.
- Gil - Shot with the Colt.
- Gregor - Stabbed in the abdomen with an angel blade.
- Kipling - Stabbed in the chest with the demon-killing knife.
- Lilith's Entourage - Killed with his psychic powers at St. Mary's Convent.
- Lucifer's Guards - Effortlessly smote with his psychic powers after drinking gallons of demon blood.
- Mailman Demon - Stabbed in the chest with the demon-killing knife.
- Mr. Richie's demon - Stabbed with the demon-killing knife.
- One of Claire's captors - Overpowered in a fight, drank some of her blood then stabbed in the chest with the demon-killing knife.
- One of Crowley's Lair Guards - Stabbed in the side with an angel blade in self-defense.
- One of the Bar Attackers - Stabbed with an angel blade.
- One of the Lucifer Loyalists - Stabbed with the demon-killing knife when it was clear the demon was worried more about killing the Winchesters than Crowley.
- One of the Tablet Hunters - Stabbed with the demon-killing knife.
- Ramiel's Protector - Stabbed in the chest with the demon-killing knife.
- Sam's Attackers - Drained their blood under the influence of Famine.
- Seven Blue Earth Demons - Killed with the demon-killing knife in Blue Earth, Montana.
- Sierra - Stabbed through the heart from behind with an angel blade.
- Sister Agnes - Stabbed through the back with the demon-killing knife while she was distracted by a recorded exorcism.
- Tom Wepram's demon - Stabbed in the chest with the demon-killing knife.
- Two of Crowley's Mansion Guards - Stabbed with the demon-killing knife.
- Multiple unnamed demons - Over the course of his career as a hunter, Sam has killed multiple unnamed demons.
Ghosts[]
Buruburu[]
- Luther Garland - Wrapped an iron chain etched in spellwork around Luther's neck enabling Bobby to drag Luther behind the Impala in a recreation of Luther's death, effectively scaring Luther to rest.
Death Omens[]
- Kate Fox - Burned her bones mistakenly believing that her ghost was killing people.
Vengeful Spirits[]
- Chester Johnson - Salted and burned the last of Chester's costumes.
- Ghost Kid - Melted the pocket knife tying the boy to the Earth with a blowtorch.
- Isabella - Salted and burned her painting.
- Jordan MacNeel - Burned the keychain tying him to the Earth.
- Jonah Greely - Salted and burned his bones.
- Marin's Brother - Burned Marin's bracelet.
- Sailor's Ghost - Summoned the spirit of his brother causing the sailor's ghost to destroy them both.
Violent Spirits[]
- Dolores Glockner - Salted and burned her bones.
- Hugo Moriarty - Salted and burned his bones.
- John Wayne Gacy - Burned his cigar box.
- Margaret Fox - Salted and burned her bones after breaking Jimmy Tomorrow's spell didn't work.
- P.T. Sandover - Burned his gloves containing some of his DNA.
Other[]
- The Sad People - Killed the Soul Eater whose Nest they were trapped in, releasing their souls to their final rests.
- Van Ness House Ghosts - Along with Dean, salted and burned the remains of Van Ness's victims so they could find peace.
- Annie Hawkins - A hunter murdered by Van Ness who requested her bones be burned so she could move on.
- Debbie Tellen - A teenager killed alongside her boyfriend while on a date at the Van Ness House.
- Debbie and Dudley's Friends - Two teenagers killed by Van Ness when they came to film a memorial to their friends.
- Dudley Scott - A teenager killed alongside his girlfriend while on a date at the Van Ness House.
- Haskel Crane - One of Van Ness's victims.
- Multiple unnamed ghosts - Over the course of his career as a hunter, Sam has put multiple unnamed ghosts to rest.
Monsters[]
Alphas[]
- Alpha Vampire - Shot through the head with the Colt.
Amazons[]
- Charlene Penn - Shot in the chest.
- Emma - Shot in the chest.
Arachne[]
- Female Arachne - Decapitated with a machete.
- Roy Dobbs - Decapitated with a machete.
Changelings[]
- Mother Changeling - Burned to ash with a flamethrower.
- Changeling Children - Killed when Sam burned their mother.
- Ben Changeling - Killed when Sam burned his mother.
- Katie Changeling - Killed when Sam burned his mother.
Crocotta[]
- Clark Adams - Killed when Sam impaled him through the back of the neck on a silver spike.
Djinn[]
- Jennifer's son - Stabbed in the heart by Sam with a silver knife dipped in lamb blood.
- One of Brigitta's Brothers - Head bashed in by Sam with a golf club.
Dragons[]
- Dragon Enforcer - Stabbed in the back with a fragment of the dragon-killing Sword of Bruncvik.
Ghouls[]
- Crowley's Ghouls - Bashed one ghoul's head in with a pipe and impaled the other through the head with the pipe during the Raid on Crowley's Monster Prison.
Hellhounds[]
- Crowley's hellhound - Sliced its chest open with the demon-killing knife.
- Ramsey - Stabbed with an angel blade.
Leviathans[]
- Edgar (permanently incapacitated) - Decapitated by Sam with a butcher knife.
- Joyce Bickleebee (permanently incapacitated) - Splashed with borax and then decapitated by Sam with a sword. Presumably devoured by George afterwards.
Musca[]
- Rogue Musca - Shot in the chest.
Qareen[]
- Sonja's Qareen - Stabbed in the heart with a small knife.
Rabids[]
- Rabid Nurse - Slit her throat with a scalpel in self-defense.
Rakshasa[]
- Barry Papazian - Impaled by Sam with a brass pipe.
Rugarus[]
- Jack Montgomery - Incinerated using a flamethrower.
Shapeshifters[]
- Bobby John's Father - Shot through the heart from behind by Sam with a silver bullet.
- Buddy - Shot in the heart by Sam with a silver bullet.
- Magnus' Shapeshifter - Stabbed in the heart by Sam with a silver knife.
Soul Eaters[]
- Michigan Soul Eater - Killed along with Dean using the Soul Eater Killing Sigil.
- Tennessee Soul Eater - Killed along with Dean using the Soul Eater Killing Sigil.
Skinwalkers[]
- One Pack Enforcer - Shot through the heart with a silver bullet
- Skinwalker Pack Leader - Shot in the face with a silver bullet.
Vampires[]
- Brett - Decapitated while rescuing Jack.
- Dark Shadows Fans - Decapitated alongside Dean.
- Gordon Walker - Decapitated with razor wire after Gordon became a vampire.
- One of Boris's nest - Decapitated on the hood of Samuel Campbell's van.
- One of Magnus' Vampires - Decapitated by Sam at Magnus' hidden house.
- Three of the Masked Vampires - Decapitated by Sam.
- Several of the Alpha Vampire's House Guards (presumably) - Sam presumably killed several of the vampires guarding the Alpha Vampire during the Campbell Family's raid to capture the Alpha Vampire.
- Jenny - Decapitated by Sam.
- Two Tunnel Vampires - Decapitated with a machete in Apocalypse World.
- Vampire Recruiter - Decapitated in the Black Rose nightclub.
- At least two unnamed vampires - Decapitated during the Raid on the British Men of Letters compound.
- Numerous unnamed vampires - Over the course of his career as a hunter, Sam has killed numerous unnamed vampires.
Vetala[]
Werewolves[]
- Brandon - Stabbed in the heart with a silver knife.
- Corbin Tilghman - Shot in the heart from behind with a silver bullet.
- Madison - Shot in the heart with a silver bullet at her request.
- Melanie - Decapitated while rescuing Jack.
- One of Corbin and Michelle's Captors - Stabbed in the heart with a silver knife.
- One of the Marina Werewolves - Shot to death with silver bullets.
- Rose - Stabbed in the heart with a silver knife.
- Rose's Bodyguard - Stabbed in the heart with a silver knife.
- Travis - Stabbed in the heart with a silver knife.
- Two of the Church Attackers - Decapitated with a machete after they proved to be immune to silver.
- Multiple unnamed werewolves - Over his career as a hunter, Sam has killed numerous werewolves.
Zombies[]
- Gerald Browder - Shot multiple times with the help of Dean and Bobby.
- Owen Mills - Shot in the head.
- Reanimated residents of Sioux Falls - Killed alongside Dean, Bobby Singer and Jody Mills.
- Several Croatoan zombies - Killed in the Raid on Niveus Pharmaceuticals.
Humans[]
British Men of Letters[]
- One member of Ketch's Assault Team - Shot in the neck during the Lockdown of the Men of Letters bunker.
- Four unnamed British operatives - Shot by Sam during the Assault on the British Men of Letters compound.
Hunters[]
- Samuel Campbell - Shot in the head while Samuel was possessed by the Khan worm.
- Steve Wandell - Slit his throat while possessed by Meg.
- Dean Winchester - Accidentally killed by Sam with an axe during Gabriel's time loop.
Psychics[]
- Jimmy Tomorrow - Shot in the chest in self-defense.
Special Children[]
- Jake Talley - Shot four times in the back and then three more in the chest.
Styne Family[]
- Jacob Frankenstein - Stabbed in the stomach with a knife after he was shot five times by Dean.
Thules[]
- Eckhart - Shot in the head with Dean and body later burned.
- One of Eckhart's henchmen - Shot in the head in Aaron Bass' rented house and body then burned.
- One Thule Hanger Guard - Neck snapped and body later burned.
Witches/Magic Practitioners[]
- Don Harding - Shot in the back multiple times alongside Dean to save Tracy Davis.
- Jeremy Frost - Bashed his head in with a baseball bat in a dreamworld, killing him in real life.
- Rowena MacLeod - Fatally stabbed at Rowena's request to complete a spell to contain the souls of Hell.
- Sonja - Shot twice with witch-killing bullets.
- Spencer Wallis - Killed with Bobby Singer's witch-killing spell alongside Dean.
- Witch Mother - Killed with the Exsanguination Spell.
Vessels[]
- Cindy McKellan - Alongside Ruby, drained the demon possessing her of all of its blood, killing both the demon and its vessel.
- Dean's Crossroad Demon's fourth vessel - Killed by Sam when he killed Dean's Crossroad Demon with the Colt.
- Josie Sands - Killed by Sam when he ignited her with holy fire to force Abaddon out.
- Lilith's vessel - Killed by Sam along with Lilith.
- Miriam's vessel - Killed by Sam along with Miriam.
- Mr. Richie - Killed by Sam along with the demon possessing him.
- Tom Wepram - Killed by Sam along with the demon possessing him.
- Alternate timeline Zachariah's vessel - Killed by Sam in an alternate timeline along with that timeline's Zachariah.
- Tyson Brady - Killed by Sam with the Demon-Killing Knife.
Regular Humans[]
- Kit Verson - Shot in the head in order to save Jemma Verson.
- Mr. Cromarty - Shot in the abdomen to save Dean.
- One of Santino Scarpatti's Bodyguards - Shot in the chest during a firefight.
- One of Sleipnir's Bodyguards - Shot in the chest during a firefight.
- Pete Garfinkle - Shot from behind to save Barrett Bishop Jr.
- Robin - Shot in the stomach in order to take away a Crossroad Demon's leverage.
Other[]
- Scarecrow - Exploded into goo after Sam killed Calliope.
- Soulless Sam - While trapped in a coma after Castiel broke the wall in his head, Sam engaged in battle with his soulless self and killed him with a shot through the back.
- Tortured Sam - While trapped in a coma after Castiel broke the wall in his head, Sam encountered a tortured version of himself bearing all of Sam's memories from Lucifer's Cage. To fully reintegrate himself, Sam killed the tortured version of himself with a knife in Bobby's kitchen.
Deities[]
- Beau - Hit in the head with Mjölnir.
- Calliope - Stabbed in the back with a blessed stake.
- Chronos - Stabbed with a 1,000 year old olive wood stake dipped in an unknown blood.
- Leshi - Decapitated with an iron axe once belonging to John Winchester.
- Madge Carrigan - Stabbed in the heart with an evergreen stake.
- Moloch - Shot with the Colt.
- Mr. Vili - Hit with Mjölnir.
- Veritas - Stabbed in the heart with a knife coated in dog blood.
Four Horsemen of the Apocalypse[]
- Famine (permanently incapacitated) - Mentally exorcised five demons out of him.
- War (permanently incapacitated) - Cut off his ring with the demon-killing knife.
Alternate realities and timelines[]
Humans[]
Hunters[]
- Jody Mills - Killed by Sam for attempting to stop him in a world where he became the leader of a demon army.
- Bobby Singer - Killed by Sam for attempting to stop him in a world where he became the leader of a demon army.
- Dean Winchester - Neck snapped with telekinesis by Sam for attempting to stop him in a world where he became the leader of a demon army.
- Unnamed hunter - Neck snapped with telekinesis by Sam for attempting to stop him in a world where he became the leader of a demon army.
- Unnamed hunter - Throat slit and stabbed in the side by Sam, after being turned into a vampire in a future where the Winchesters locked God away.
Monsters[]
Vampires[]
- Benny Lafitte - Killed by Sam for attempting to stop him in a world where he became the leader of a demon army.
Non-Canon[]
Deities[]
- Adamantine - Forced her own silver gauntlet into her stomach alongside Dean.
- Armament - Blasted with his own shotgun alongside Dean.
Monsters[]
Aswang[]
- Dozens of unborn Aswang - Destroyed their eggs with the stingray barb of a specially-made whip.
Harpies[]
- Podrage - Shot through the heart with Bobby's rifle, allowing Bobby to plant a knife in her heart, keeping her incapacitated until he, Sam and Dean could burn the harpies bodies, killing them.
- Te - Shot twice through the heart with Bobby's rifle, allowing Dean to plant a knife in her heart, keeping her incapacitated until he, Sam and Bobby could burn the harpies bodies, killing them.
Jakkals[]
- Erin Monsour - Stabbed through the heart with a gold blade in self defense.
Night Hags[]
- Olga's Night Hag - Stabbed with a makeshift iron short-spear after tricking the night hag into feeding on him, rendering her vulnerable to harm.
Shtriga[]
- Unnamed Shtriga - Shot through the head with an iron round as it was feeding on Samuel Campbell.
Vampires[]
- Four unnamed vampires - Two decapitated with a chainsaw in Port Reyes Station and two more decapitated on a cliff side with an ice axe when they came for revenge.
Werewolves[]
- Alan Crowder - Shot in the heart with silver bullets alongside Dean.
- Sylvia Crowder - Shot in the heart with silver bullets alongside Dean.
Ghosts[]
Vengeful Spirits[]
- Several ghosts of the Forty Year - Killed during the third murder cycle by rock salt rounds or their own weapons.
Violent Spirits[]
- The Rifleman - Spirit laid to rest alongside Dean.