Killed by Sam Winchester

“	I'm stronger than that now. Now I can kill.	”
	— Sam prepares to kill Alastair in On The Head Of A Pin

“	I've killed innocent people in the line of duty. But I'm pretty sure it's not something the old me could've done. And maybe I should feel guilty. But I don't.	”
	— Soulless Sam to Dean Winchester in All Dogs Go To Heaven

Beings killed by Sam Winchester.

Angels

Higher Angels

• Alternate timeline Zachariah - Stabbed in the heart with an angel blade.

Regular Angels

• One of Arthur and Charlie's Captors - Stabbed in the chest with an angel blade.
• Miriam - Stabbed through the heart with an angel blade.

Demons

Princes of Hell

• Ramiel - Stabbed in the heart with the Lance of Michael, causing him to explode into dust.

Crossroad Demons

• Dar (presumably) - Presumably killed after torturing her for information on Dean's whereabouts.
• Dean's Crossroad Demon - Shot in the head with the Colt when she wouldn't break Dean's deal.
• Robin's captor - Killed during Sam's soulless period.
• Unnamed Crossroad Demon - Killed with the demon-killing knife after he wouldn't trade Sam's soul for Dean's.

White-eyed demons

• Alastair - Tortured and killed with his powers as one of the Special Children.
• Lilith - Killed with his powers as one of the Special Children. Required all of the demon blood from one demon and more from another.

Regular Demons

• Blood Source Demons - Throats slit by Sam with the demon-killing knife in order to collect all of their blood.
• Brady - Stabbed in the stomach with the demon-killing knife.
• Bunker Incursion Demons - Stabbed one with an angel blade. Killed three others alongside Castiel and Gabriel.
• Carl's demon - Stabbed in the chest with the demon-killing knife.
• Casey - Shot with the Colt.
• Cindy McKellan's demon - Alongside Ruby, drained of blood to power his abilities.
• Four Iowa Factory Guards - Vaporized with a demon bomb.
• Four Nebraska Factory Guards - Two stabbed with an angel blade and two vaporized with a demon bomb.
• Gil - Shot with the Colt.
• Gregor - Stabbed in the abdomen with an angel blade.
• Kipling - Stabbed in the chest with the demon-killing knife.
• Lilith's Entourage - Killed with his psychic powers at St. Mary's Convent.
• Lucifer's Guards - Effortlessly smote with his psychic powers after drinking gallons of demon blood.
• Mailman Demon - Stabbed in the chest with the demon-killing knife.
• Mr. Richie's demon - Stabbed with the demon-killing knife.
• One of Claire's captors - Overpowered in a fight, drank some of her blood then stabbed in the chest with the demon-killing knife.
• One of Crowley's Lair Guards - Stabbed in the side with an angel blade in self-defense.
• One of the Bar Attackers - Stabbed with an angel blade.
• One of the Lucifer Loyalists - Stabbed with the demon-killing knife when it was clear the demon was worried more about killing the Winchesters than Crowley.
• One of the Tablet Hunters - Stabbed with the demon-killing knife.
• Ramiel's Protector - Stabbed in the chest with the demon-killing knife.
• Sam's Attackers - Drained their blood under the influence of Famine.
• Seven Blue Earth Demons - Killed with the demon-killing knife in Blue Earth, Montana.
• Sierra - Stabbed through the heart from behind with an angel blade.
• Sister Agnes - Stabbed through the back with the demon-killing knife while she was distracted by a recorded exorcism.
• Tom Wepram's demon - Stabbed in the chest with the demon-killing knife.
• Two of Crowley's Mansion Guards - Stabbed with the demon-killing knife.
• Multiple unnamed demons - Over the course of his career as a hunter, Sam has killed multiple unnamed demons.

Ghosts

Buruburu

• Luther Garland - Wrapped an iron chain etched in spellwork around Luther's neck enabling Bobby to drag Luther behind the Impala in a recreation of Luther's death, effectively scaring Luther to rest.

Death Omens

• Kate Fox - Burned her bones mistakenly believing that her ghost was killing people.

Vengeful Spirits

• Chester Johnson - Salted and burned the last of Chester's costumes.
• Ghost Kid - Melted the pocket knife tying the boy to the Earth with a blowtorch.
• Isabella - Salted and burned her painting.
• Jordan MacNeel - Burned the keychain tying him to the Earth.
• Jonah Greely - Salted and burned his bones.
• Marin's Brother - Burned Marin's bracelet.
• Sailor's Ghost - Summoned the spirit of his brother causing the sailor's ghost to destroy them both.

Violent Spirits

• Dolores Glockner - Salted and burned her bones.
• Hugo Moriarty - Salted and burned his bones.
• John Wayne Gacy - Burned his cigar box.
• Margaret Fox - Salted and burned her bones after breaking Jimmy Tomorrow's spell didn't work.
• P.T. Sandover - Burned his gloves containing some of his DNA.

Other

• The Sad People - Killed the Soul Eater whose Nest they were trapped in, releasing their souls to their final rests.
• Van Ness House Ghosts - Along with Dean, salted and burned the remains of Van Ness's victims so they could find peace.
  • Annie Hawkins - A hunter murdered by Van Ness who requested her bones be burned so she could move on.
  • Debbie Tellen - A teenager killed alongside her boyfriend while on a date at the Van Ness House.
  • Debbie and Dudley's Friends - Two teenagers killed by Van Ness when they came to film a memorial to their friends.
  • Dudley Scott - A teenager killed alongside his girlfriend while on a date at the Van Ness House.
  • Haskel Crane - One of Van Ness's victims.

Monsters

Alphas

• Alpha Vampire - Shot through the head with the Colt.

Amazons

• Charlene Penn - Shot in the chest.
• Emma - Shot in the chest.

Arachne

• Female Arachne - Decapitated with a machete.
• Roy Dobbs - Decapitated with a machete.

Changelings

• Mother Changeling - Burned to ash with a flamethrower.
• Changeling Children - Killed when Sam burned their mother.
  • Ben Changeling - Killed when Sam burned his mother.
  • Katie Changeling - Killed when Sam burned his mother.

Crocotta

• Clark Adams - Killed when Sam impaled him through the back of the neck on a silver spike.

Djinn

• Jennifer's son - Stabbed in the heart by Sam with a silver knife dipped in lamb blood.
• One of Brigitta's Brothers - Head bashed in by Sam with a golf club.

Dragons

• Dragon Enforcer - Stabbed in the back with a fragment of the dragon-killing Sword of Bruncvik.

Ghouls

• Crowley's Ghouls - Bashed one ghoul's head in with a pipe and impaled the other through the head with the pipe during the Raid on Crowley's Monster Prison.

Hellhounds

• Crowley's hellhound - Sliced its chest open with the demon-killing knife.
• Ramsey - Stabbed with an angel blade.

Leviathans

• Edgar (permanently incapacitated) - Decapitated by Sam with a butcher knife.
• Joyce Bickleebee (permanently incapacitated) - Splashed with borax and then decapitated by Sam with a sword. Presumably devoured by George afterwards.

Musca

• Rogue Musca - Shot in the chest.

Qareen

• Sonja's Qareen - Stabbed in the heart with a small knife.

Rabids

• Rabid Nurse - Slit her throat with a scalpel in self-defense.

Rakshasa

• Barry Papazian - Impaled by Sam with a brass pipe.

Rugarus

• Jack Montgomery - Incinerated using a flamethrower.

Shapeshifters

• Bobby John's Father - Shot through the heart from behind by Sam with a silver bullet.
• Buddy - Shot in the heart by Sam with a silver bullet.
• Magnus' Shapeshifter - Stabbed in the heart by Sam with a silver knife.

Soul Eaters

• Michigan Soul Eater - Killed along with Dean using the Soul Eater Killing Sigil.
• Tennessee Soul Eater - Killed along with Dean using the Soul Eater Killing Sigil.

Skinwalkers

• One Pack Enforcer - Shot through the heart with a silver bullet
• Skinwalker Pack Leader - Shot in the face with a silver bullet.

Vampires

• Brett - Decapitated while rescuing Jack.
• Dark Shadows Fans - Decapitated alongside Dean.
• Gordon Walker - Decapitated with razor wire after Gordon became a vampire.
• One of Boris's nest - Decapitated on the hood of Samuel Campbell's van.
• One of Magnus' Vampires - Decapitated by Sam at Magnus' hidden house.
• Three of the Masked Vampires - Decapitated by Sam.
• Several of the Alpha Vampire's House Guards (presumably) - Sam presumably killed several of the vampires guarding the Alpha Vampire during the Campbell Family's raid to capture the Alpha Vampire.
• Jenny - Decapitated by Sam.
• Two Tunnel Vampires - Decapitated with a machete in Apocalypse World.
• Vampire Recruiter - Decapitated in the Black Rose nightclub.
• At least two unnamed vampires - Decapitated during the Raid on the British Men of Letters compound.
• Numerous unnamed vampires - Over the course of his career as a hunter, Sam has killed numerous unnamed vampires.

Vetala

• Marlene - Stabbed in the heart with a silver knife by Sam which he then twisted.

Werewolves

• Brandon - Stabbed in the heart with a silver knife.
• Corbin Tilghman - Shot in the heart from behind with a silver bullet.
• Madison - Shot in the heart with a silver bullet at her request.
• Melanie - Decapitated while rescuing Jack.
• One of Corbin and Michelle's Captors - Stabbed in the heart with a silver knife.
• One of the Marina Werewolves - Shot to death with silver bullets.
• Rose - Stabbed in the heart with a silver knife.
• Rose's Bodyguard - Stabbed in the heart with a silver knife.
• Travis - Stabbed in the heart with a silver knife.
• Two of the Church Attackers - Decapitated with a machete after they proved to be immune to silver.
• Multiple unnamed werewolves - Over his career as a hunter, Sam has killed numerous werewolves.

Zombies

• Gerald Browder - Shot multiple times with the help of Dean and Bobby.
• Owen Mills - Shot in the head.
• Reanimated residents of Sioux Falls - Killed alongside Dean, Bobby Singer and Jody Mills.
• Several Croatoan zombies - Killed in the Raid on Niveus Pharmaceuticals.

Humans

British Men of Letters

• One member of Ketch's Assault Team - Shot in the neck during the Lockdown of the Men of Letters bunker.
• Four unnamed British operatives - Shot by Sam during the Assault on the British Men of Letters compound.

Hunters

• Samuel Campbell - Shot in the head while Samuel was possessed by the Khan worm.
• Steve Wandell - Slit his throat while possessed by Meg.
• Dean Winchester - Accidentally killed by Sam with an axe during Gabriel's time loop.

Psychics

• Jimmy Tomorrow - Shot in the chest in self-defense.

Special Children

• Jake Talley - Shot four times in the back and then three more in the chest.

Styne Family

• Jacob Frankenstein - Stabbed in the stomach with a knife after he was shot five times by Dean.

Thules

• Eckhart - Shot in the head with Dean and body later burned.
• One of Eckhart's henchmen - Shot in the head in Aaron Bass' rented house and body then burned.
• One Thule Hanger Guard - Neck snapped and body later burned.

Witches/Magic Practitioners

• Don Harding - Shot in the back multiple times alongside Dean to save Tracy Davis.
• Jeremy Frost - Bashed his head in with a baseball bat in a dreamworld, killing him in real life.
• Rowena MacLeod - Fatally stabbed at Rowena's request to complete a spell to contain the souls of Hell.
• Sonja - Shot twice with witch-killing bullets.
• Spencer Wallis - Killed with Bobby Singer's witch-killing spell alongside Dean.
• Witch Mother - Killed with the Exsanguination Spell.

Vessels

• Carl - Killed by Sam along with the demon possessing him.

• Cindy McKellan - Alongside Ruby, drained the demon possessing her of all of its blood, killing both the demon and its vessel.
• Dean's Crossroad Demon's fourth vessel - Killed by Sam when he killed Dean's Crossroad Demon with the Colt.
• Josie Sands - Killed by Sam when he ignited her with holy fire to force Abaddon out.
• Lilith's vessel - Killed by Sam along with Lilith.
• Miriam's vessel - Killed by Sam along with Miriam.
• Mr. Richie - Killed by Sam along with the demon possessing him.
• Tom Wepram - Killed by Sam along with the demon possessing him.
• Alternate timeline Zachariah's vessel - Killed by Sam in an alternate timeline along with that timeline's Zachariah.
• Tyson Brady - Killed by Sam with the Demon-Killing Knife. 

Regular Humans

• Kit Verson - Shot in the head in order to save Jemma Verson.
• Mr. Cromarty - Shot in the abdomen to save Dean.
• One of Santino Scarpatti's Bodyguards - Shot in the chest during a firefight.
• One of Sleipnir's Bodyguards - Shot in the chest during a firefight.
• Pete Garfinkle - Shot from behind to save Barrett Bishop Jr.
• Robin - Shot in the stomach in order to take away a Crossroad Demon's leverage.

Other

• Scarecrow - Exploded into goo after Sam killed Calliope.
• Soulless Sam - While trapped in a coma after Castiel broke the wall in his head, Sam engaged in battle with his soulless self and killed him with a shot through the back.
• Tortured Sam - While trapped in a coma after Castiel broke the wall in his head, Sam encountered a tortured version of himself bearing all of Sam's memories from Lucifer's Cage. To fully reintegrate himself, Sam killed the tortured version of himself with a knife in Bobby's kitchen.

Deities

• Beau - Hit in the head with Mjölnir.
• Calliope - Stabbed in the back with a blessed stake.
• Chronos - Stabbed with a 1,000 year old olive wood stake dipped in an unknown blood.
• Leshi - Decapitated with an iron axe once belonging to John Winchester.
• Madge Carrigan - Stabbed in the heart with an evergreen stake.
• Moloch - Shot with the Colt.
• Mr. Vili - Hit with Mjölnir.
• Veritas - Stabbed in the heart with a knife coated in dog blood.

Four Horsemen of the Apocalypse

• Famine (permanently incapacitated) - Mentally exorcised five demons out of him.
• War (permanently incapacitated) - Cut off his ring with the demon-killing knife.

Alternate realities and timelines

Humans

Hunters

• Jody Mills - Killed by Sam for attempting to stop him in a world where he became the leader of a demon army.
• Bobby Singer - Killed by Sam for attempting to stop him in a world where he became the leader of a demon army.
• Dean Winchester - Neck snapped with telekinesis by Sam for attempting to stop him in a world where he became the leader of a demon army.
• Unnamed hunter - Neck snapped with telekinesis by Sam for attempting to stop him in a world where he became the leader of a demon army.
• Unnamed hunter - Throat slit and stabbed in the side by Sam, after being turned into a vampire in a future where the Winchesters locked God away.

Monsters

Vampires

• Benny Lafitte - Killed by Sam for attempting to stop him in a world where he became the leader of a demon army.

Non-Canon

Deities

• Adamantine - Forced her own silver gauntlet into her stomach alongside Dean.
• Armament - Blasted with his own shotgun alongside Dean.

Monsters

Aswang

• Dozens of unborn Aswang - Destroyed their eggs with the stingray barb of a specially-made whip.

Harpies

• Podrage - Shot through the heart with Bobby's rifle, allowing Bobby to plant a knife in her heart, keeping her incapacitated until he, Sam and Dean could burn the harpies bodies, killing them.
• Te - Shot twice through the heart with Bobby's rifle, allowing Dean to plant a knife in her heart, keeping her incapacitated until he, Sam and Bobby could burn the harpies bodies, killing them.

Jakkals

• Erin Monsour - Stabbed through the heart with a gold blade in self defense.

Night Hags

• Olga's Night Hag - Stabbed with a makeshift iron short-spear after tricking the night hag into feeding on him, rendering her vulnerable to harm.

Shtriga

• Unnamed Shtriga - Shot through the head with an iron round as it was feeding on Samuel Campbell.

Vampires

• Four unnamed vampires - Two decapitated with a chainsaw in Port Reyes Station and two more decapitated on a cliff side with an ice axe when they came for revenge.

Werewolves

• Alan Crowder - Shot in the heart with silver bullets alongside Dean.
• Sylvia Crowder - Shot in the heart with silver bullets alongside Dean.

Ghosts

Vengeful Spirits

• Several ghosts of the Forty Year - Killed during the third murder cycle by rock salt rounds or their own weapons.

Violent Spirits

• The Rifleman - Spirit laid to rest alongside Dean.