| “ | She saw me when I was scouting out the bunker. She saw me and she screamed, and then so I crushed her skull with my bare hands. And it was warm and wet, and I liked it. | ” |
| “ | Hey, snapping necks and cashing checks is what I do. | ” |
Beings killed by Lucifer.
Angels[]
Seraphim[]
- Castiel - Stabbed through the back with an angel blade; resurrected by the Shadow.
Cherubim[]
- Unnamed Cherub - Punched a hole through his chest after stealing his grace.
Regular Angels[]
- Angel Commander - Exploded at the molecular level.
- Angel Commander's Henchmen - Exploded at the molecular level.
- Castiel - Exploded at the molecular level in revenge for hitting Michael with holy fire; resurrected by God as a Seraphim.
- Jofiel - Exploded at the molecular level.
- Nithael - Exploded at the molecular level.
- Road Attackers - Exploded at the molecular level.
- Several of Michael's angels - Grace consumed and then killed.
Demons[]
Regular Demons[]
- Around a dozen demons - Sacrificed as part of a ritual to summon Death.
- Castiel and Lucifer's Attackers - Killed alongside Castiel with an angel blade in Crowley's old lair.
- Rachel Nave and several other demons - Killed by Lucifer to give Sam revenge for the demons spying on him his whole life under the orders of Azazel.
- Thomas and his friend - Exploded both at the molecular level.
- Unnamed demons - Killed to take their blood to power vessel.
Humans[]
Hunters[]
- Alternate reality hunter - Punched his fist through his body.
- Bobby Singer - Neck snapped with telekinesis; resurrected by Castiel.
- Maggie - Head bashed in; resurrected by Lucifer on Jack's request.
Vessels[]
- Archbishop - Body burned out through Lucifer's possession.
- Jimmy Novak - Killed when Lucifer exploded Castiel.
- Nick - Body burned out through Lucifer's possession. Resurrected by Crowley to serve as Lucifer's permanent vessel.
- Unnamed family of four - Bodies burned out through Lucifer's possession.
- Lucifer's Father Vessel - Father of the family burned out by Lucifer's possession.
- Lucifer's Mother Vessel - Mother of the family burned out by Lucifer's possession.
- Lucifer's Teenage Vessel - Son of the family burned out by Lucifer's possession.
- Lucifer's Sister Vessel - Daughter of the family burned out by Lucifer's possession.
- Lucifer's temporary vessel - Body burned out through Lucifer's possession.
- Vince Vincente - Body burned out through Lucifer's possession.
- Wallace Parker - Body burned out through Lucifer's possession.
- Nithael's Vessel - Killed when Lucifer exploded Nithael.
- Jofiel's Vessel - Killed when Lucifer exploded Jofiel.
- Cupid's Vessel - Heart ripped out while under possession.
- Demon Blood hosts - Killed to take their enhanced blood.
Witches/Magic Practitioners[]
- Rowena MacLeod - Neck snapped; resurrected through a spell; killed again by stomping her head in and then incinerating her body; resurrected again by her spell.
Regular Humans[]
- Bill - Induced an aneurism.
- Father Davis - Exploded at the molecular level.
- Gordy and Adam - Necks snapped with telekinesis.
- Priests and nuns of St. Louis, Missouri - Brutally slaughtered.
- Residents of Carthage, Missouri - Sacrificed as part of a ritual to summon Death.
- Russel Lemmons - Telekinetically stabbed with a pen.
- Sarah (caused) - Brutally murdered by Abraxas with a hammer on Lucifer's orders.
- Teddy (caused) - Brutally murdered by Abraxas with a hammer on Lucifer's orders.
- Tommy - Neck snapped with telekinesis.
- Unnamed Priest - Exploded at the molecular level.
- Vince's band mates - Necks snapped with telekinesis.
- Thousands of unnamed humans during The Apocalypse - Killed personally or caused.
Other[]
Deities[]
- Baldur - Punched through the chest.
- Baron Samedi - Brutally slaughtered.
- Ganesh - Exploded at the molecular level.
- Isis - Brutally slaughtered.
- Mercury - Telekinetically snapped his neck.
- Odin - Brutally slaughtered.
- Two unnamed deities - Brutally slaughtered.
- Gods - Killed for sovereignty over the Earth (distant past)
Reapers[]
- Betty - Stabbed in the chest with an angel blade; reincarnated as the new Death; turned to ash.
Alternate realities and timelines[]
Humans[]
- Humanity - Killed in alternate 2014 future timeline through usage of the Four Horsemen of The Apocalypse, demon armies, Croatoan Zombies. (caused)
Hunters[]
- Future Dean Winchester - Neck snapped in 2014 by an alternate timeline Lucifer after Dean failed to kill him with the Colt.
- Alternate Dean Winchester - Burned alive by an alternate reality Lucifer after shooting Lucifer through the head with the Colt and failing to kill him.