Jake Tanner is the brother of Duane Tanner.
Jake and his father were infected with the Croatoan Virus, and he also infected his mother with it. His father was killed by Dean Winchester. Jake got away because Sam did not shoot him. He tried to kill Dean with other town people that were infected with the virus.
Later on, he and other infected townspeople formed a road block, preventing anyone, including Dean, from getting out. He and the other men attempted to attack Dean but Dean managed to escape.
Presumably, Jake and these men escaped the town, unharmed.
- Nolan Gerard Funk and Diego Klattenhoff, the actors portraying Jake Tanner and his brother Duane, also portrayed two brothers in the CW series Smallville.