Indestructibility

Amara can be harmed, but it is almost impossible to destroy her

Indestructibility is the property to be beyond destruction, no matter how powerful an attempt to destroy this object or entity is.

Characters with this ability

All characters are listed in alphabetical order.

Nigh Indestructibility

These supernatural entities or objects that are next to indestructible and can only be killed or destroyed by beings of the same level of power or higher.

• Cain - As the bearer of the Mark of Cain and the very first Knight of Hell, he can't be killed by normal means. Only with the First Blade by another wielder of the Mark of Cain could he be killed.
• Dean (formerly) - As the bearer of the Mark of Cain and as a Knight of Hell he can't be killed by normal means; only the power of The First Blade or The Darkness can kill him. God and Death can also kill him but not before they remove the Mark and as human he can be killed only to be resurrected again as Knight of Hell.
• Lucifer (formerly) - Since Lucifer once bore the Mark of Cain, he was almost indestructible.
• Death - Death had a considerable immunity against nearly all kind of physical and supernatural attacks. Could only be killed by his own scythe.
• Famine, Pestilence, and War - Although their physical bodies could be damaged, and the Horsemen themselves could be weakened, they couldn't be destroyed but by a handful of weapons and beings.
• God - God is close to indestructible; only the Darkness and Death could kill him.
• Souls - Death admitted that the soul cannot be broken not even by him. However the souls can be converted into demons which makes them vulnerable to certain beings and weapons. Also it has been stated that the Darkness could destroy everything including souls.
• The First Blade - The First Blade can't be destroyed by any known means.
• The Darkness - After a combined attack from angels, demons, and witches, Amara was still standing (albeit barely). Even after being struck by Lucifer following the combined attack, she still managed to overpower both Lucifer and God, as well as mortally wound the latter. Her only possible weakness is light equivalent to 10,000 suns going supernova at once or the Soul Bomb.
• Yokoth - Stated to be completely impossible to kill her even after nearly a hundred years of trying.

Advanced Indestructibility

These beings are among the most resilient and powerful in the Supernatural universe, they have very few weaknesses and could only be killed by nigh-omnipotent forces or very rare and powerful weapons.

• Archangels - Archangels are immune to almost all known forms of physical harm, save for a handful of weapons.
• Eve - Eve existed in Purgatory for a long time, and was related to Leviathans. Only one substance was said to be able to kill her.
• Knights of Hell - Powerful demons trained by Cain, they were resistant even to the Demon-Killing Knife. Only the First Blade is confirmed to be able to kill them.
• Leviathans - Nigh-indestructible beasts created by God, one of them survived having a car dropped on it. Only the Bone of Righteous Mortal Washed in the Three Bloods of Fallen is confirmed to be able to kill them.

Medium Indestructibility

These Supernatural beings have certain vulnerabilities, and could also be killed be some higher-tier entities like archangels.

• Angels - Angels can't be harmed but by a few weapons and beings. Their vessels, while occupied, are virtually indestructible, as long as the means by which the vessel is harmed doesn't affect the angel.
• Azazel - A Prince of Hell. He was completely immune to holy water and salt, in addition to other immunities shared by demons.
• Deities - According to Sam, while they were still worshiped, they were next to invincible. Despite having lost most of their worshipers, however, they are still almost indestructible.
• Fairies - Fairies are immune to several forms of harm.
• Nephilim - As the offspring between an angel and a human, Nephilim are very resilient to physical damage.
• Samhain - The unique multicolored Demon Samhain showed little pain when cut by the Demon-Killing Knife, which is excruciating even to a Knight of Hell.
• The Wicked Witch - She was almost impossible to destroy, as even things that killed regular witches had no effect on her.
• White-eyed Demons - They were highly resistant to salt and holy water. They couldn't be killed by Ruby's Knife as well as a regular angel's smiting.
• Whore of Babylon - The Whore was invulnerable to almost every known form of physical harm.

Low Indestructibility

These Supernatural beings have certain non-physical vulnerabilities, but they could also be killed be a lot of higher-tier entities like angels or powerful demons.

• Alphas - Alphas are immune to everything their children are immune to, and are more resilient to their weaknesses as well. Some Alphas are immune to weaknesses their children share.
• Black-eyed and Red-eyed demons - Despite being at the low end of the demonic hierarchy, as demons, they are almost impossible to destroy. Most harm to their vessel is irrelevant, as a demon can survive even if their vessel is damaged beyond its ability to stay alive.
• Dragons - Dragons can shrug off almost any physical attack.
• Hellhounds - Although they can be hurt by firearms and common demonic weaknesses, Hellhounds are extremely resilient to damage, even that inflicted by their own kind.
• Jefferson Starships - As hybrids, they share the strengths (and immunities) of their "pure" counterparts.
• Jesse Turner - As the hybrid of a demon and a human, Jesse was vulnerable to everything demons were vulnerable to.
• Nachzehrer - Nachzehrer are "already dead", so decapitation and other forms of physical attack can't destroy them.
• Phoenix - A Phoenix can't be killed by hanging, gunfire, or other forms of physical attack.
• Siren - Sirens are very resilient to most known forms of destruction.
• Vampires - Vampires are immune to almost all physical harm, including stakes and bullets.

Minimal Indestructibility

These supernatural beings have many vulnerabilities, and can often be killed by conventional means like fire, beheading, silver knives, and higher-tier entities.

• Amazons - Despite their strength and other abilities, Amazons are as vulnerable as any human.
• Arachne - Arachne are impervious to bullets and fire.
• Changelings - Changelings are highly resistant to damage.
• Djinn - Djinn are resilient to bullets.
• Ghouls - Ghouls can shrug off most physical attacks.
• Kitsune - Kitsune can't be destroyed by physical attacks.
• Okami - Okami can't be killed by conventional weapons.
• Pishtaco - They are invulnerable to most physical attacks.
• Rawhead - Invulnerable to physical attacks.
• Shtriga - Shtriga are invulnerable to all forms of weaponry unless they're feeding.
• Skinwalkers - They possess most of the invulnerabilities of werewolves, which include gunfire, knives, and most other types of physical attacks.
• Wendigo - Wendigo can't be harmed by physical attacks.
• Werewolf - Werewolves can shrug off almost any physical attack.
• Witch - Despite their supernatural abilities, witches, like Amazons, are as vulnerable as humans.
• Wraith - Wraiths can't be destroyed by most weapons.