Keyes was born in Detroit and raised in Flint. He began his career appearing on stage productions and also worked as model and fitness trainer. He has made his screen debut appearing in small role in 2005 comedy-drama film Diary of a Mad Black Woman starring Kimberly Elise.
On television, he has had guest starring roles on Brothers & Sisters, Moonlight, Family Time, Beauty and the Beast, Instant Mom, Mistresses and Born Again Virgin. From 2011 to 2014, Keyes had a recurring role in the BET comedy series Let's Stay Together. He also appeared in Keri Hilson's music video "Energy" and "The Way That I Love You" by Ashanti, playing love interests.
Keyes has appeared in several films and made-for-television movies, include leading roles in Perfect Combination (2010), Lord, All Men Can't Be Dogs (2011), Note to Self (2012), Act Like You Love Me (2013) and The Man in 3B (2015). He also appear in a Tyler Perry's stage plays including "Madea Goes To Jail" and "What's Done in the Dark".
In 2016, Keyes was cast as male lead alongside Vanessa Bell Calloway, Gloria Reuben, Jasmine Burke and Clifton Powell in the Bounce TV prime time soap opera, Saints & Sinners.