The Loop (TV)
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Blood is an important component in many rituals, weapons, spells, and other aspects of the supernatural world.
Rituals and spells
- Creating an Angel Banishing Sigil: Requires Human blood or Angel blood.
- Using the Goblet of Blood: Requires fresh blood from a human victim.
- Summoning a demon that was previously exorcised: Requires the blood of the original exorcist. (Repo Man)
- Angel-tracking ritual: This ritual, which Castiel uses to track down Balthazar, requires human blood. (The Third Man)
- Soul-proofing spell: Requires the blood of the soulless person's father - or the equivalent of a father. The father must also be killed. (Appointment In Samarra)
- Summoning Samhain: Requires three blood sacrifices. (It's the Great Pumpkin, Sam Winchester)
- Opening a portal to Purgatory: Requires the blood of a creature native to Purgatory.
- Binding spell: Kali used Sam and Dean's blood to cast a spell that prevented them from escaping outside the field/area of her prescence (the hotel). (Hammer of the Gods)
- Binding Death: Part of the ritual to summon and bind Death requires the blood of the summoner. (Meet The New Boss)
- Curing Vampirism: The ritual to change a newly-sired vampire back into a human requires the blood of the vampire that infected him/her. Also, if the victim has already drunk human blood, the ritual will not work. (Live Free or Twihard)
- Bone Of Righteous Mortal Washed In the Three Bloods of Fallen: Requires blood from a Fallen Angel, an Alpha, and the current King of Hell.
- Dead Man's Blood: Can be used to incapacitate Vampires.
- Vamp-Tonite: It will kill Vampires, Werewolves, Ghouls, Shapeshifters and other creatures that eat humans, except for Leviathan. (There Will Be Blood)
- Sword of Bruncvik: Forged in Dragon's blood. The only thing that can kill Dragons. (Like A Virgin)
- Leviathan blood is fatal to Angels and possibly other creatures. (Reading Is Fundamental)
- Djinn can only be killed by a silver knife dipped in lamb's blood.
- Veritas could only be killed with a knife dipped in a dog's blood. (You Can't Handle The Truth)
- Chronos could only be killed by an olive stake dipped in the blood of "You don't want to know." (Time After Time)
- Tricksters can only be killed by a stake dipped in the blood of one of their recent victims.
- Sirens can only be killed by a bronze dagger dipped in the blood of someone under their spell. (Sex and Violence)
- Angelic Possession: Angels, especially Archangels, typically only possess humans of certain bloodlines, such as the Winchester bloodline. Although this is not necessarily required, as evidenced by Lucifer's possession of Nick, who's certainly not related to the Winchesters, vessels that are not of proper bloodlines will deteriorate over time.
- Croatoan Virus: The virus is passed on through blood contact.
- Food: Certain creatures, namely vampires, vetala, and djinn live off the blood of humans. Some demons, like Lilith, also drink human blood for fun.
- Vampiric reproduction: Humans can be transformed into vampires by ingesting vampiric blood.
- Demon blood is needed to charge the Special Children's powers, as well as for a vessel to contain Lucifer.
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