Castiel uses Dean's blood to track down Balthazar.

Blood is an important component in many rituals, weapons, spells, and other aspects of the supernatural world.


Rituals and spells

721 Angel sigil

An angel Banishing Sigil drawn in human blood.

  • Creating an Angel Banishing Sigil: Requires Human blood or Angel blood.
  • Using the Goblet of Blood: Requires fresh blood from a human victim.
  • Summoning a demon that was previously exorcised: Requires the blood of the original exorcist. (Repo Man)
  • Angel-tracking ritual: This ritual, which Castiel uses to track down Balthazar, requires human blood. (The Third Man)
  • Soul-proofing spell: Requires the blood of the soulless person's father - or the equivalent of a father. The father must also be killed. (Appointment In Samarra)
  • Summoning Samhain: Requires three blood sacrifices. (It's the Great Pumpkin, Sam Winchester)
  • Opening a portal to Purgatory: Requires the blood of a creature native to Purgatory.
  • Binding spell: Kali used Sam and Dean's blood to cast a spell that prevented them from escaping outside the field/area of her prescence (the hotel). (Hammer of the Gods)
  • Binding Death: Part of the ritual to summon and bind Death requires the blood of the summoner. (Meet The New Boss)
  • Curing Vampirism: The ritual to change a newly-sired vampire back into a human requires the blood of the vampire that infected him/her. Also, if the victim has already drunk human blood, the ritual will not work. (Live Free or Twihard)



Dead Man's Blood

Other uses

Jimmy possessed

Castiel possessing Jimmy Novak

  • Angelic Possession: Angels, especially Archangels, typically only possess humans of certain bloodlines, such as the Winchester bloodline. Although this is not necessarily required, as evidenced by Lucifer's possession of Nick, who's certainly not related to the Winchesters, vessels that are not of proper bloodlines will deteriorate over time.
  • Croatoan Virus: The virus is passed on through blood contact.
  • Food: Certain creatures, namely vampires, vetala, and djinn live off the blood of humans. Some demons, like Lilith, also drink human blood for fun.
  • Vampiric reproduction: Humans can be transformed into vampires by ingesting vampiric blood.
  • Demon blood is needed to charge the Special Children's powers, as well as for a vessel to contain Lucifer.

See Also

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