User blog comment:MarkManeMcIntyre/Death being Dead?/@comment-26992577-20160505131733/@comment-26992577-20160505143206

Okay, let's say they end up in the empty and the mere process causes some kind of supernatural disturbances all around creation (The same was the case, when the Darkness was released). Maybe this would destroy the cage and a crazy Michael escapes or the event will cause supernatural anomalies everywhere / resurrects all old villains (Azazel, Lilith, Dick, ...). There are countless possibilities and all the two major forces (Amara & Chuck) can never again take influence on the events outside the empty. Death is also dead. The Winchesters would be completely on their own this time (And no, they aren't always: Season 3: Defeated by Lilith, later rescued by Castiel. Season 4: Sam killed Lilith - as God intended but only to release Lucifer. Season 5: God& Death helped them. Season 6: Castiel destroyed the old villain to become the new one. Season 7: God powered weapon killed Dick. Season 8: There was nothing special. Season 9: Amara powered weapon killed Abbadon. Season 10: Using a divine spell to make things even worse (or better- I don't think Amara is that evil)).