Alpha Vampire

The Alpha Vampire was the very first Vampire and progenitor of all other vampires. He escaped Crowley's prison and set up a new nest in North Dakota then Montana.

Early Life
His human form is of African descent. It is unknown exactly how old he is, but he mentions he was the thing in the dark when humans built fire (presumably early humans), so it's most likely that he is tens of thousands of years old. When asked, he admitted to knowing a about the Leviathans, correlating to his age. He was created by Eve, like the all other Alpha monsters.

He created an entire race of Vampires across the world that soon populated into a new civilization. He kept close tabs on his "children" while continuing to populate the world with Vampires for many years.

Season 6
In "Live Free or Twihard", The Alpha Vampire is first glimpsed briefly flashing in the minds of its "children" as it commands them to recruit more for its army. Nothing is known about this particular monster, aside from the fact its "messages" can be heard by all vampires and render them unconscious. Dean Winchester sees this vision while he is infected.

In "Family Matters", Samuel and his people capture the Alpha Vampire. They subdue him using an I.V. of Dead Man's Blood and attempt to interrogate him, but he is extremely resistant to pain and gives Samuel no information. After Samuel leaves the room where he is being held, the alpha is approached by Dean and Sam. He reveals to them that, though he is the first vampire, he has a mother. He recognizes Dean and he seems interested in Sam's soullessness.

He also tells them that Samuel is torturing him for information about Purgatory and where it is located. Shortly after their conversation, he breaks out of his cage and almost escapes, but demons appear and take him away on Crowley's orders. It is revealed that Samuel has been working for Crowley, who will continue to question the Alpha Vampire about the location of Purgatory.

In "All Dogs Go To Heaven", when Crowley asks Sam and Dean to find another Alpha, Sam and Dean ask if the Alpha Vampire was not enough for him. It is probable that Crowley could not get any information out of him as he is extremely resistent to pain and torture.

Powers and Abilities
The Alpha Vampire has all the traits and abilities of normal vampires, although they are phenomenally enhanced.
 * Immortality - The Alpha will live forever, provided he has a steady supply of blood and is not decapitated.
 * Superhuman Senses - Enhanced sight, hearing, and smell.
 * Superhuman Physical Traits - Enhanced strength, speed, agility, durability, stamina, healing, stealth.
 * His strength is such that it took three demons to restrain him, even after being continually filled with dead man's blood and right after receiving two further doses of dead man's blood directly to the neck. He was even able to assault Edgar, a high-ranking Leviathan.
 * He ranks as one the fastest creatures seen on the show, barring those who can teleport.

Abilities exclusive to him -
 * The Alpha had the ability to sense that Sam had no soul. It may be linked to his sense of smell, seeing as how he remarked "you smell cold" to Sam; but he may not have meant this literally.
 * The Alpha was able to make his fingernails grow at will, extending them long enough to cut through his bonds.

He possesses all of the Alpha enhanced physical abilities -
 * Enhanced Pain Threshold - The Alpha Vampire has demonstrated a drastically augmented pain threshold, easily enduring any and all forms of torture that Samuel or Crowley could devise.
 * Family Ties: As the progenitor of his race, the Alpha can find his "children" all across the globe, and can sense when they are born and die. He was even aware that Dean had been turned and learned his name, and also knew that he was cured.
 * Telepathy - The Alpha Vampire can communicate telepathically with all of its "children" (Dean called it his "psychic bat-signal"). Connecting with his children has an effect on them. When the Alpha contacted the vampires in Boris's nest and Dean (which may have been a world-wide communication), they were each filled a sense of euphoria and lost consciousness for the duration of his abstract visual message. Apparently, this ability can be stunted by pumping enough dead man's blood into his system.
 * Connection to the the Mother of All - Although all monsters have a connection to Eve, the Alphas seem to have a more direct link to her, even across dimensions. Through this connection, she was able to give the Alpha Vampire orders to prepare for the upcoming war, and to "recruit" more monsters. He was also privy to her location, Purgatory, and how to find it.

Weaknesses

 * Dead man's blood
 * Decapitation (presumed)

Appearances

 * Season 6
 * Live Free or Twihard
 * Family Matters
 * All Dogs Go To Heaven (mentioned only)
 * Season 7
 * There Will Be Blood

Trivia

 * What the Alpha Vampire represents in the show would be Dracula in lore, however Supernatural has a separate character for him.