User blog comment:Thetwindler/Which class of demon is the most powerful?/@comment-1031724-20190325033716/@comment-31767970-20190326055139

Thetwindler, i don't think that they are easier but at that moment in the series where the knights were introduced, the only option (The First Blade), was the hardest, they didn't had the Colt, Sam's powers, Jack's powers, Gabriel's powers, Michael's spear, etc. I belive that any option above could kill any knight, including Cain (the mark would ressurect him but he would indeed die before).