Killed by Dean Winchester

"What a gift not to recall the things you've done! (...) You're a killer Dean Winchester. (...) Scores."

- Rowena MacLeod telling a memory-less Dean Winchester about his kills. Beings killed by Dean Winchester.

Archangels

 * Lucifer - Stabbed in the heart with an archangel blade while powered by Michael.

Higher Ranking Angels

 * Zachariah - Stabbed through the head with an angel blade.

Regular Angels

 * Executioner Angel - Shot with angel-killing bullets alongside Arthur Ketch.
 * One of Arthur and Charlie's Captors - Stabbed in the side with an angel blade.
 * Prison Camp Angels - Shot with angel-killing bullets alongside Arthur Ketch.
 * Rogue Angel - Stabbed through the back with his own angel blade.

Princes of Hell

 * Azazel - Shot in the heart with the Colt.

Knights of Hell

 * Abaddon - Stabbed in the stomach with the First Blade.
 * Cain - Stabbed in the back with the First Blade.

Regular Demons

 * Abaddon Loyalist - Stabbed with the First Blade.
 * Allen House Demon - Stabbed with the demon-killing knife outside Daphne Allen's house.
 * Astaroth - Stabbed several times in the side with the demon-killing knife.
 * Bar Demon - Stabbed with the demon-killing knife.
 * Christian Campbell Demon - Stabbed through the back with the demon-killing knife.
 * Cop Demon - Stabbed through the throat with the demon-killing knife after seeing the demon's true face.
 * Drew Neely demon - Stabbed with the First Blade.
 * Eunis' demon - Stabbed in the chest with the demon-killing knife by Dean after a reverse exorcism is performed on her by Sam.
 * Gardener Demon - Stabbed in the chest with the demon-killing knife.
 * Harrington - Flung an angel blade through his neck.
 * Hotel Assassins - Stabbed with the demon-killing knife while chasing after Rowena MacLeod.
 * Humboldt Hotel Guard - Stabbed with the First Blade during the Battle of the Humboldt Hotel.
 * Linda's Attacker - Stabbed in the chest with the demon-killing knife.
 * Five of Lisa and Ben's Captors - Stabbed with the demon-killing knife while rescuing Lisa and Ben.
 * Marco - Stabbed with the demon-killing knife after Marco refused to talk and it was determined that his vessel was dead.
 * Meg's Minion - Stabbed in the chest with the demon-killing knife.
 * Four Nebraska Factory Guards - Stabbed with the demon-killing knife and vaporized with a demon bomb while rescuing Samandriel.
 * One of Nick's Henchmen - Stabbed in the chest with an angel blade while rescuing Donatello Redfield.
 * Niveus Guard - Stabbed with the demon-killing knife inside the Niveus Pharmaceuticals building.
 * One of the Blue Earth Demons - Stabbed with the demon-killing knife in Blue Earth, Montana.
 * One of the Convenience Store Demons - Stabbed with the demon-killing knife inside a convenience store.
 * One of the Iowa Factory Guards - Stabbed with the demon-killing knife while rescuing the future Prophets.
 * Rodger's demon - Slit his throat with the demon-killing knife.
 * Ruby - Stabbed in the stomach with the demon-killing knife.
 * Spanky - Stabbed in the chest with the demon-killing knife by Dean.
 * Three of Dean's Captives - Captured and tortured for information on the location of Lisa and Ben before killing them with the demon-killing knife when they wouldn't talk.
 * Tom - Shot through the head with the Colt.
 * Two members of Abaddon's Demon Army - Killed along with the Bar Demon with the demon-killing knife in a brawl at Cain's house.
 * Two of the Bar Attackers - Stabbed with an angel blade.
 * Viggo - Stabbed with the demon-killing knife while rescuing Samandriel.
 * Wally's Attacker - Stabbed through the back with an angel blade outside of Ramiel's house.
 * Multiple unnamed demons - Over the course of his career as a hunter, Dean has killed multiple unnamed demons.

Death Omens

 * Isaiah Merchant - Salted and burned his bones after mistakenly believing Isaiah to be committing the murders committed by Melanie Merchant.
 * Leticia Gore - Salted and burned her bones after believing her to be harming guests at the first Supernatural convention.

Specters

 * Vance Collins - Salted and burned his bones which combined with Garth Fitzgerald IV melting the penny he was attached to destroyed Vance.

Vengeful Spirits

 * Cyrus Dorian - Lured his ghostly truck onto hallowed ground, destroying it and his ghost.
 * Dirk MacGregor, Jr. - Burned the lock of hair tying Dirk to the Earth after he began possessing students and harming bullies.
 * Mary Worthington - Showed Mary her reflection causing Mary's own powers to destroy her.
 * The Witnesses - Completed a spell performed by Bobby Singer to put the Witnesses to rest.

Violent Spirits

 * Avery Meadows - Burned the plague masks Meadows was attached to.
 * Jacob Karns - Salted and burned his bones followed by melting down the objects Karns' silver hook had been reforged into.
 * Melanie Merchant - Burned the doll containing the lock of hair binding Melanie to the Earth.
 * Sanford Ellicott - Salted and burned his remains in the Roosevelt Asylum.
 * Whitman Van Ness - Salted and burned his bones after discovering his house containing trapped ghosts.

Other

 * Avery Meadows' victims - Sent to their respective afterlives by the Reaper Jessica due to Dean's deal with Billie.
 * Evan - Sent to Heaven by the Reaper Jessica due to Dean's deal with Billie.
 * Shawn Raider - Sent to Heaven by the Reaper Jessica due to Dean's deal with Billie.
 * Bobby Singer - Burned Bobby's Flask and put him to rest on Bobby's request after he briefly became a vengeful spirit.
 * Mordechai Murdoch - A Tulpa inadvertently created by Ed Zeddmore and Harry Spangler that took the form of a ghost due to the legend surrounding Murdoch. Burned down the house that was part of Murdoch's legend, destroying him.
 * The Sad People - Killed the Soul Eater whose Nest they were trapped in, releasing their souls to their final rests.
 * Van Ness House Ghosts - Along with Dean, salted and burned the remains of Van Ness's victims so they could find peace.
 * Annie Hawkins - A hunter murdered by Van Ness who requested her bones be burned so she could move on.
 * Debbie and Dudley's Friends - Two teenagers killed by Van Ness when they came to film a memorial to their friends.
 * Debbie Tellen - A teenager killed alongside her boyfriend while on a date at the Van Ness House.
 * Dudley Scott - A teenager killed alongside his girlfriend while on a date at the Van Ness House.
 * Haskel Crane - One of Van Ness's victims.
 * Dozens of unnamed ghosts - Over the course of his career as a hunter, Dean has put to rest dozens of ghosts.

Soul Eaters

 * Michigan Soul Eater - Killed along with Sam using the Soul Eater Killing Sigil.
 * Tennessee Soul Eater - Killed along with Sam using the Soul Eater Killing Sigil.

Djinn

 * Jennifer O'Brien - Stabbed in the back by Dean with a silver knife dipped in lamb blood.
 * Neil - Head bashed in by Dean with a heavy metal bookend and then Dean fired several shots into his head to ensure that Neil was dead.
 * Unnamed Djinn - Stabbed in the back by Dean with a silver knife dipped in lamb blood.

Fairies

 * A Tink - Fried by Dean in a microwave.

Ghouls

 * Adam Ghoul - Head bashed in by Dean.
 * Kate Ghoul - Decapitated by Dean with a shotgun blast.
 * Unnamed Ghoul - Beaten to death with a baseball bat wrapped in barbed wire.

Gog and Magog's Species

 * Gog - Stabbed through the back with Magog's Sword.
 * Magog - Decapitated with Magog's Sword.

Bisaan

 * Bisaan Guard - Decapitated by Dean with a shovel.

Jefferson Starships

 * Unnamed Jefferson Starship - Decapitated by Dean after it attempted to attack Castiel.

Siren

 * Unnamed Siren - Beaten to death with a baseball bat wrapped in barbed wire.

Hellhounds

 * One member of Meg's Hellhound Pack - Shot by Dean with the Colt in Carthage, Missouri.

Kitsune

 * Amy Pond - Stabbed in the heart by Dean.

Lamia

 * An unnamed Lamia - Threw a mixture of rosemary and salt onto it and then set it on fire with a lit gas line.

Leviathans

 * At least three Leviathans in Purgatory (permanently incapacitated) - Decapitated in defense of himself, Castiel and Benny Lafitte.
 * Dick Roman - Stabbed through the neck with the Bone of Righteous Mortal Washed in the Three Bloods of Fallen with the help of Castiel.
 * Leviathan Dean (permanently incapacitated) - Splashed with borax and decapitated with a fire axe.
 * Leviathan Sam (permanently incapacitated) Splashed with borax by Sheriff Osborne then decapitated by Dean with a fire axe.
 * Royce (permanently incapacitated) - Decapitated at SucroCorp.

Nachzehrer

 * Deputy Donelly - A Nachzehrer killed by Dean when he stuffed pennies down Donelly's throat and then decapitated him with the Impala's rear door.

Phoenix

 * Elias Finch - Shot in the heart with the Colt in order to get his ashes to use against Eve.

Pishtaco

 * Alonso - Severed his proboscis with a silver knife.

Edward Trenton's Species

 * Edward Trenton - Throat slit by Dean with a silver-coated steel knife after being transformed into an unknown species of monster.

Rawhead

 * Unnamed Rawhead - Electrocuted to death by Dean with a taser, but as it was standing in a puddle of water that Dean was sitting in at the time, he received a fatal electric shock as well.

Rugaru

 * Purgatory Rugaru - A rugaru interrogated by Dean in Purgatory for the location of Castiel. Killed by Dean stabbing the demon-killing knife into his brain.

Shapeshifters

 * Olivia - Shot through the heart from behind with a silver bullet and then shot several more times.
 * Robbery Shapeshifter - Stabbed in the heart with a silver letter opener.
 * Serial Killer Shapeshifter - Shot twice in the heart with silver bullets.

Shōjō

 * Dale's Shōjō - Stabbed through the chest with a katana that had a Shinto Blessing on it.

Shtriga

 * Hydeker - A shtriga killed by Dean with a consecrated wrought-iron round to the head as he's feeding on Sam.

Skinwalkers

 * Four Pack Enforcers - Shot with silver bullets from a rifle and his pistol.
 * Pack Leader's Second in Command - Shot in the heart by Dean with a silver bullet from a rifle.

Vampires

 * Alpha Vampire's Male Guard - Injected in the neck with vamptonite.
 * An unnamed vampire nest of six members - Decapitated off-screen by Dean.
 * At least four vampirates - Decapitated by Dean with his Purgatory Blade during the Battle of Prentiss Island.
 * Beau - Decapitated in Luther's nest.
 * Boris's nest - Wiped out after being temporarily turned into a vampire.
 * Boris - Decapitated in his nest after being temporarily transformed into a vampire.
 * Robert - Decapitated while taking out Boris's nest.
 * Kristen Powell (presumably) Presumably killed along with the other vampires in Boris's nest.
 * Celia's Family - Wiped out alongside Jody Mills.
 * Celia's Son - Injected in the heart with dead man's blood and later decapitated.
 * Connor - Decapitated with the help of the Mark of Cain.
 * Dale - Decapitated in his nest.
 * Conrad - Decapitated to save Gordon Walker.
 * Dixon (presumably) - Presumably decapitated at his own request.
 * Reggie's Friend - Decapitated outside of a cabin.
 * Gordon's Victim - Shot in the head with the Colt.
 * Impala Vampire - Decapitated on the hood of the Impala.
 * Andrea Kormos - Decapitated with his Purgatory Blade to save Benny.
 * Kris (presumably) - Presumably killed after promising to "make it quick" if she told him where the rest of her nest went.
 * Benny Lafitte - Decapitated so Benny could rescue Sam from Purgatory.
 * Len's nest - Wiped out alongside Donna Hanscum.
 * Catfish - Decapitated in a barn.
 * An unnamed vampire - Decapitated inside a barn.
 * Lucy - Reluctantly decapitated after she was transformed into a vampire by Dixon.
 * Maurice - Decapitated to save the life of Ennis Ross.
 * One of Magnus' Vampires - Decapitated by Dean at Magnus' hidden house.
 * Purgatory Vampire - Decapitated with his Purgatory Blade.
 * Reggie - Decapitated by Dean with a machete.
 * Richard Beesome - Decapitated to protect Claire Novak and Alex Jones.
 * Two Tunnel Vampires - One decapitated with a machete, blew the other's head off with a shotgun.
 * Two Vampires from a Purgatory nest - Decapitated with Dean's Purgatory Blade.
 * Dozens of unnamed vampires - Over the course of his tenure as a hunter, Dean has killed dozens of vampires during his hunts.

Wendigo

 * Colorado Wendigo - Incinerated with a flare gun.

Werewolves

 * Glen - Shot three times with silver bullets.
 * Jobah - Stabbed in the heart with a silver knife.
 * Joy Myers - Shot in the heart with a silver bullet.
 * One of the Marina Werewolves - Shot to death with silver bullets.
 * One of Corbin and Michelle's Captors - Stabbed with a silver knife after he shot Sam.
 * Professor Ludensky - Shot in the heart with a silver bullet.
 * Russ - Stabbed through the heart with a silver knife from behind.
 * Sheriff Pat - Stabbed in the heart with a silver knife.
 * Multiple unnamed werewolves - Over the course of his career as a hunter, Dean has killed multiple unnamed werewolves.

Khan worms

 * Original Khan Worm - Electrocuted to death by Dean while possessing Bobby Singer.
 * Two Variant Khan Worms - Crushed by Dean after emerging from Kit Verson and Cole Trenton.

Wraith

 * Nurse Foreman - Stabbed in the heart with a silver-plated letter opener.
 * Psychic Attacker - Stabbed in the side with a silver knife.
 * Unnamed Wraith - Beaten to death with a baseball bat wrapped in barbed wire.

Zombies

 * Angela Mason - Staked in the heart to her coffin with a silver stake.
 * Beverly Tanner - Shot by Dean while she was infected with the Croatoan Virus.
 * Clay Thompson - Shot in the head by Dean.
 * Gerald Browder - Shot multiple times with the help of Sam and Bobby.
 * Mr. Tanner - Shot by Dean while infected with the Croatoan Virus.
 * Pamela Clayton - Shot by Dean while she was infected with the Croatoan Virus.
 * Two Cemetery Zombies - Both staked in the heart with silver stakes.
 * Two reanimated residents of Sioux Falls - Shot in the head by Dean.
 * Vance - Staked in the heart to his coffin with a silver stake alongside Jack.

Hunters

 * Gwen Campbell (indirectly caused) - Shot in the chest while possessed by the khan worm.
 * Himself (twice) - First time: Overdosed on drugs. Revived by Dr. Kessler. Second time: Injected himself with poison. Resurrected by Billie.
 * Rudy (caused) - Caused Reggie to stab him in the chest by startling the vampire while he was holding a knife to Rudy's chest.

Styne Family

 * Cyrus Frankenstein - Shot in the head by Dean in the Men of Letters bunker.
 * Eldon Frankenstein - Shot in the head in revenge for the murder of Charlie Bradbury.
 * Eldon's Henchman - Stabbed in the neck by Dean.
 * Eli Frankenstein - Throat slashed by Dean with a bone saw.
 * Jacob Frankenstein - Shot in the chest five times before he was stabbed in the stomach by Sam.
 * Monroe Frankenstein - Neck snapped by Dean.
 * One of Jacob's Henchmen - Unloaded a pistol clip into him.
 * Roscoe Frankenstein - Stabbed in the spine with a knife by Dean in the Men of Letters bunker.
 * Styne Mansion Guards - One stabbed in the neck by Dean, another shot in the head, a third shot twice in the back at point-blank range.
 * Styne Nurse - Injected in the neck by Dean with her own syringe.
 * Over a dozen unnamed family members - Brutally killed by Dean during the Styne Family Massacre.

British Men of Letters

 * Two members of Ketch's Assault Team - Shot in the head by Dean during the Lockdown of the Men of Letters bunker.

Thules

 * A Thule Hangar Guard - Neck snapped by Dean and body later burned.
 * Adolf Hitler - Shot in the head by Dean while possessing Commandant Nauhaus whose body was later burned.
 * Commandant Nauhaus - Shot in the head by Dean while possessed by Adolf Hitler and his body later burned.
 * Eckhart - Shot in the head with Sam and body later burned.
 * Gottfried - Shot in the head by Dean and his body later burned.
 * One of Eckhart's henchmen - Shot in the head by Dean in Aaron Bass's rented house.
 * Thule Assassin - Killed by Dean outside of a diner where he was waiting to ambush the Winchesters and his body later burned.
 * Wolfgang - Shot in the head by Dean and his body later burned.

Vessels

 * Alastair's second vessel - Inflicted multiple fatal injuries upon while torturing Alastair that the man died of when Alastair was killed.
 * Drew Neely - Killed by Dean empowered by The Mark of Cain along with the demon possessing him.
 * Eunis - Killed by Dean along with the demon possessing her.
 * Eve's vessel - Killed when Dean tricked Eve into biting him, poisoning her with Phoenix ash.
 * Human April Kelly - Killed when Dean stabbed the Reaper possessing her in the chest with an angel blade.
 * Josie Sands (possibly) - If Josie was resurrected when Abaddon restored her body, she was killed for a second time when Dean killed Abaddon.
 * Marco's vessel - Killed when Dean stabbed Marco in the chest with the demon-killing knife.
 * Rodger - Killed when Dean slit the demon possessing him's throat with the demon-killing knife.
 * Rogue Angel's vessel - Killed when Dean stabbed the Rogue Angel through the back with an angel blade.
 * Tammi Fenton - Killed by Dean with the demon-killing knife along with Astaroth.
 * Tom's vessel - Shot through the head with The Colt when Dean killed the demon possessing him.
 * Unnamed Cop - Stabbed through the throat with the demon-killing knife along with the demon possessing him.
 * Zachariah's vessel - Killed when Dean stabbed Zachariah through the head with an angel blade.

Witches/Magic Practitioners

 * Borrower Witch - Shot in the chest with a witch-killing bullet.
 * Boyd Loughlin - Shot in the chest with a witch-killing bullet.
 * Catriona Loughlin - Shot in the head with a witch-killing bullet.
 * Don Harding - Shot in the back multiple times alongside Sam to save Tracy Davis.
 * Gideon Loughlin - Shot in the abdomen with a witch-killing bullet, bled out.
 * Howard - Dean used Howard's own ritual to summon the ghost of his brother who drowned Howard.
 * Katja - Incinerated in her own oven.
 * Leo - Mauled by a pack of dogs summoned by Dean.
 * Magnus - Decapitated with the First Blade.
 * Randa Moreno, Paul Hayes, Jimmy Tong and the five other people with Inyo's organs - Killed when Dean stabbed Randa in the heart.
 * Spencer Wallis - Killed alongside Sam with Bobby Singer's witch-killing spell.

Regular Humans

 * Girl in the walls' Brother - Shot three times by Dean in self-defense.
 * Hansel - Stabbed in the chest with a butcher knife by Dean.
 * Hilary - Killed her by using the power of Death's Ring in order to fix the natural order.
 * Jeffrey - Shot twice in the chest by Dean.
 * Lester Morris - Stabbed in the chest with the First Blade.
 * One of Sleipnir's Bodyguards - Shot in the chest during a firefight.
 * Randy, Salinger and three of Salinger's men - Slaughtered by Dean under the influence of the Mark of Cain.
 * Richard Greenstreet's Bodyguard - Shot in the chest.
 * Roger - Stabbed in the chest with his own knife by Dean.
 * Terrance Clegg - Shot through the heart from behind by Dean to save Sam.
 * Terry - Shot through the back to stop him from killing Sam with Chrysayor.
 * Yeager - Shot by an alternate reality Dean due to being infected with the Croatoan Virus.

Others

 * Eve - Tricked into ingesting phoenix ash.
 * Self-Loathing Dean - Shot twice with a sawed-off shotgun in the nightmare he was trapped in by Jeremy Frost.
 * Whore of Babylon - Impaled with an oak stake from Babylon.

Deities

 * Edward Carrigan - Stabbed in the heart with an evergreen stake.
 * Zao Shen - Stabbed in the back with a stake.

Four Horsemen of the Apocalypse

 * Death - Impaled through the side with his own scythe.

Reapers

 * April Kelly - Stabbed in the chest with an angel blade.
 * Maurice - Stabbed through the throat with an angel blade.

Twigs and Twine Clones

 * Andy - Dissolved into a pile of twigs and twine after Dean killed the witch that created him.
 * Rick Walsh - Dissolved into a pile of twigs and twine after Dean killed the witch that created him.
 * Tasha Banes - Dissolved into a pile of twigs and twine after Dean killed the witch that created her.

Aswang

 * Jason - Impaled in the heart with the stingray barb of a specially-made whip.

Ghouls

 * Darrell Carson - Decapitated with a machete.
 * Kate Carson - Decapitated with a machete.
 * Lori Carson - Decapitated with a machete.
 * Phillip Carson - Decapitated with a machete.

Oni

 * Dalton Rourke - Shot through his third eye.
 * Jesse Trumball - Stabbed through his third eye and into his brain with a crowbar.

Pontianak

 * Riza Nodd - Decapitated her after Sam put Riza to sleep with a railroad spike through the back of her neck.

Vengeful Spirits

 * Clive Gillmer - Salted and burned his remains.
 * George Drechler - Salted and burned his bones.
 * Ghosts manifested by The Forty Year - Killed several during the third murder cycle of the Forty Year. Put the remaining to rest using a counterspell from John Winchester's Journal combined with a salt and burn of Elizabeth Claire Marbrough's bones performed by Juliet Monroe.
 * The Last Calusa - Destroyed using the combined spiritual power of the ghosts of Key West.