Blood



Blood is an important component in many rituals, weapons, spells, and other aspects of the supernatural world.

Rituals and spells

 * Creating an Angel Banishing Sigil: Requires Human blood or Angel blood
 * Using the Goblet of Blood: Requires fresh blood from a human victim.
 * Summoning a demon that was previously exorcised: Requires the blood of the original exorcist. (Repo Man)
 * Angel-tracking ritual: This ritual, which Castiel uses to track down Balthazar, requires human blood. (The Third Man)
 * Soul-proofing spell: Requires the blood of the soulless person's father - or the equivalent of a father. The father must also be killed. (Appointment In Samarra)
 * Summoning Samhain: Requires three blood sacrifices. (It's the Great Pumpkin, Sam Winchester)
 * Opening a portal to Purgatory: Requires the blood of a creature native to Purgatory.
 * Binding spell: Kali used Sam and Dean's blood to cast a spell that prevented them from escaping the hotel. (Hammer of the Gods)
 * Binding Death: Part of the ritual to summon and bind Death requires the blood of the summoner. (Meet The New Boss)

Weapons

 * Bone Of Righteous Mortal Washed In the Three Bloods of Fallen: Requires blood from a Fallen Angel, an Alpha, and the current King of Hell.
 * Dead Man's Blood: Can be used to incapacitate Vampires.
 * Vamp-Tonite: It will kill Vampires, Werewolves, Ghouls, Shapeshifters and other creatures that eat humans, except for Leviathan. (There Will Be Blood)
 * Sword of Bruncvik: Forged in Dragon's blood. The only thing that can kill Dragons. (Like A Virgin)
 * Leviathan blood is fatal to Angels and possibly other creatures. (Reading Is Fundamental)
 * Djinn can only be killed by a silver knife dipped in lamb's blood.
 * Veritas could only be killed with a knife dipped in a dog's blood. (You Can't Handle The Truth)
 * Chronos could only be killed by an olive stake dipped in the blood of "You don't want to know." (Time After Time)
 * Tricksters can only be killed by a stake dipped in the blood of one of their recent victims.
 * Sirens can only be killed by a bronze dagger dipped in the blood of someone under their spell. (Sex and Violence)

Other uses

 * Angelic Possession: Angels typically only possess humans of certain bloodlines, however it's not required, as evidenced by Lucifer possessing Nick, who's certainly not a relation to the Winchesters. This is especially true of the Archangels.
 * Croatoan Virus: The virus is passed on through blood contact.
 * Food: Certain creatures, namely Vampires and Vetala live off the blood of humans. Some demons, like Lilith, also drink human blood.
 * Vampiric reproduction: Humans can be transformed into vampires by ingesting vampiric blood.
 * Demon blood is needed to charge the Special Children's powers, as well as for a vessel to contain Lucifer.