Pestilence

Pestilence is the fourth and final of The Four Horsemen of the Apocalypse to be featured on the show. Not much is known about him at present since he has not yet made an official appearance on the show. However, actor Matt Frewer has been confirmed to portray Pestilence in the upcoming Episode 20 of Season 5, where he will get his own debut as have his three brothers: War, Death, and Famine.

It is presumed that, like his three brothers, Pestilence's power is channeled and controlled by use of a special glass ring he possesses, and that the only way to impede him is to separate him from this ring. As his name implied, Pestilence has power over anything that can inflict pain or misery on the Earth, such as infestations, plagues, and most prominently diseases. He is said to ride on a white horse, but as his brothers have all "gotten with the times", he is likely to travel in some kind of white automobile alluding to his association with the color white from Biblical lore. It is unknown how he will demonstrate his powers in Episode 20, though foreshadowing from The End seems to give a small hint at what Pestilence may do: the Croatoan virus, shown to possibly be Lucfier's endgame for the human race in The End, most certainly falls under the power of Pestilence as it is a viral epidemic. Given that Pestilence makes his debut near the end of Season 5, this further adds to this possibility.