Anne Whitting

Anne Whitting is one of the descendants of the set to die patrons of the titanic, whose creation was made possible by the angel Castiel through the angel Balthazar's intervening powers.

She was ultimatley killed in a tragic accident orchestrated by the fate Atropos.

She was meant to serve as a fighting soul soldier in Castiel's army against renegade angel Raphael.

Anne appears in the Season 6 episode My Heart Will Go On.

By the end of the episode to which she appears in Balthazar travels back in time and doesn't interfere in the Titanic's chosen route resulting in Anne's ancestor dying aboard the ship and her birth never coming into existence.

She is portrayed by actress Jill Morrison.

Background
Anne Whitting serves as a travel agent in Pennsylvania who was distributing holidays to Cuba at her Pennsylvania State Office when the Greek Fate Atropos came and froze time to orchestrate an accident to claim her life.

She was killed as after Atropos froze time she had her car keys thrown underneath the office photocopier she was tending to and upon attempting to retrieve them had her scarf get caught in the pull of the machine, and ultimatley strangle her to death.

Anne Whitting is a descendant of a patron of the infamous ship the Titanic and was never meant to exist creation wise as the Titanic patron of whom she descends from was meant to die aboard the doomed voyage but was saved through the intervention of angels Castiel and Balthazar.

Anne had then gone on to be born and raised in Pennsylvania and eventually became a prestigious travel agent.

The crime scene of her death was investigated by Sam Winchester and Dean Winchester who eventually caught onto Balthazar and Castiel's plan as well as the acting Atropos who set up Anne's execution.

Anne's entire existence was eventually reversed in the end as Castiel ordered Balthazar to travel back in time and allow the Titanic to make it's collision with the iceberg which would destroy the ship and kill her ancestor.