User blog comment:ImperiexSeed/The oldest being, archangel or leviathan?/@comment-3481504-20120516180343/@comment-3481504-20120516214151

Yes, they can, but NOT Archangels.

...But have Sam or Dean plunged, kicked, or punched Deities to death? No, the answer is no. But Lucifer has.

No, no, no. Eve isn't immune to their power, that why she shot it off. Leviathans are, however. But not to Archangels.