User blog comment:Fusedtwilight/SEASON 8!!!!!!/@comment-76.212.203.216-20120519030939/@comment-76.212.203.216-20120519062850

No, the Horsemen of the Apocalypse would indeed be significantly more powerful at least when they are at full power, ImperiexSeed. To be more suspefic, Cthulhu would be directly beneath the Horsemen in the same power level. However, it's ultimately the writers and producers' discretion to how powerful Cthulhu would be if he were to ever appear in Supernatural.