Chimera

Chimera is legendary monster with parts from multiple random animals and humans. It featured in Supernatural: Cold Fire.

Overview
A Chimera, somehow unleashed to a factory at unnamed county in USA. While it continuously infect people, it also attack a heavy squad of security officers. Sam and Dean went to the factory to end the imminent threat. However, it later revealed that the chimera has been constituted an army of chimeric human-beasts such as Minotaur, snake-woman, ape-human, lobster-human, etc. large enough to decimate a nearby town. They later forced to eliminate the nest before all being too late.

However, they realized, if the source of the infection was the Chimera blood. Any direct contact with its blood will mutated the part of body which contacted to random part of animals. After trying to culling the mutation by cutting the infected part, they found if the part soon decayed. Sam and Dean later deduced if the mutation affect are tied to Chimera, and newly turned will easily cured, since the part will not regenerate. They later decided to kill the Chimera to end the crisis.

Power and Abilities
This Chimera, being constituted by multiple parts from multiple random animals and humans, are very formidable. Its mutation affect also very dangerous, because it will transform human to human-animal hybrids the point it couldn't recoverable.
 * Infectious blood - Chimera blood is highly infectious, and could induced mutation to human. Every human that contact with its blood will get infected and mutated into random animal part.
 * Mutation - Chimera could induce mutation process, making human into human-animal hybrids.

Weaknesses

 * Culling - Culling the infected will slow down the mutation process, but if the blood has been spread too far inside the human bodies, it will not help.
 * Beheading - Beheading the chimera effectively kill him and their turned mobs. Beheading the "pack alpha" head chimera will cure the newly turned. But if the infection has been take a long while, killing them is the only solution, since no cure for the infection.

Appearance

 * Supernatural: Cold Fire