User blog comment:Noctosphere/any hope for season 12?/@comment-1975828-20160815013537

Hybrids tend to have an one-episode appearance, like Jesse Turner and Jane, so I wouldn't get my hopes up.

I don't think she is dead. She is most likely very old and still alive, but they could very well change that. I too have hopes that she will appear.

Death is dead. Reapers are said to be angry at the Winchesters. Only Billie the Reaper is a friend/ally.