User blog comment:Twilight Despair 5/New Plots/@comment-3045936-20180529203200/@comment-74.132.82.188-20180531020217

Sure, why not? If the British Men of Letters came over to the US gunning for the Winchesters, why wouldn´t monsters want to kill them, too?

If they can use Osiris, Zeus, etc, in a few episodes, why not bring back the mythical baddies--Medusa and her Gorgon sisters,  Minotaurs, Chimera, etc. Maybe we could be worried about Pandora´s box or the Fates running rampant. Gods like Ammit, who devoured souls, and Shesmu could fit, too. Still, there are some cool monsters available.

And why can´t Eve escape from purgatory? She wouldn´t be the first character who´s resurrected and she could create new monsters like she did the Khan worm and bring through some old ones.

I agree, though, that it would be an awkward transition from resolving Michael and re-populating Heaven to Eve.