Mark of Cain

The Mark of Cain is the source of The First Blade's power. It is one half of the weapon that Cain used against the rest of the Knights of Hell. Cain later transferred the mark to Dean, so that the hunter could kill Abaddon.

When Dean used the First Blade for the first time, he felt a murderous rage that did not dissipate after he killed a victim with it. It later gave him immunity to Abaddon's powers and telekinesis and have a telekinetic control of the blade, all with great concentration, allowing him to overcome and kill her. After killing Abaddon, this rage caused him to mutilate her corpse. He also displayed superhuman strength while fighting a vampire.

When the bearer of the Mark receives a mortal wound that would kil them, the mark transforms their soul into a Knight of Hell, so that it can live on, and never perish.

Effects of the mark
The mark embules its bearer wth several great powers.
 * Super Strength - The mark grants the bearer enough strength to overpower a vampire and shrug out of an angel's hold. Dean was able to effortlessly hoist Abaddon into the air when jabbing her with the blade.
 * Murderous Rage - The mark affects the bearer to where they constantly must kill something, if they don't they'll eventually die as pointed out by Crowley. Cain, as a demon, was totally unaffected by this and could go forever with the mark without killing.
 * Telekinesis - The mark grants the bearer the ability to summon the blade to the hand that calls it.
 * Resurrection - The mark, if the wearer dies, will resuscitate the bearer back to life as a demon.
 * Immunity - The mark allows the wearer immunity to demonic powers, as shown by Dean resisting Abaddon's telekinesis.
 * Super Stamina - The mark greatly enhnces its bearers stamina, Dean was able to go without sleep or food for several days with no ill affects.

Appearances

 * Season 9
 * First Born 
 * Sharp Teeth
 * The Purge (Mentioned only)
 * Blade Runners
 * Mother's Little Helper (Flashbacks/Mentioned)
 * Meta Fiction
 * King of the Damned
 * Stairway To Heaven
 * Do You Believe In Miracles?