User blog comment:EmpyreanSmoke/Supernatural Q&A/@comment-26992577-20150920192640/@comment-24834479-20150920203836

There were a lot of ideas floating around the writers room about that, but none of them are carved in stone. If white eyed demons are randomly produced, then yes, there probably will be

(My own theory: White eyed = pure souls corrupted (before humans ate the fruit Red eyes = Made a deal and sold your soul to Hell Yellow eyes = angel stripped of grace, and twisted into a demon Black eyes = Damned to Hell because of the life you led)