First Blood

First Blood is the 9th Episode of Season 12. It aired on January 26, 2017.

Summary
THE HUNTERS BECOME THE HUNTED – After being arrested for the attempted assassination of the President of The United States, Sam (Jared Padalecki) and Dean (Jensen Ackles) must find a way out of an underground, government-run, detention facility in the middle of nowhere. Determined to find her sons, Mary (guest star Samantha Smith) and Castiel (Misha Collins) seek assistance from an unlikely source.

Main Cast

 * Jared Padalecki as Sam Winchester
 * Jensen Ackles as Dean Winchester
 * Misha Collins as Castiel
 * Mark Sheppard as Crowley

Reccuring Cast

 * Samantha Smith as Mary Winchester
 * Lisa Berry as Billie
 * Stephen Lobo as Rick Sanchez
 * David Haydn-Jones as Arthur Ketch
 * Adam Fergus as Mick Davies
 * Kara Royster as Alicia Banes (voice only)

Featured Supernatural Beings

 * Seraph (Castiel)
 * Crossroad Demon (Crowley)
 * Reaper (Billie)
 * Vampire  (cameo)

Continuity

 * Billie is killed in the episode. This marks the death of another recurring reaper since Tessa.
 * Sam briefly dies in this episode. This is his first death since he fell into Lucifer's Cage in Swan Song.
 * Dean previously died in Red Meat when he committed suicide so he could speak to Billie. Similarly, Dean had attempted to make a deal with her to revive Sam, whom he thought had died.

Trivia

 * This is the 250th episode.
 * This was watched by 1.72 million viewers and got a 0.6 rating.
 * "First Blood" is a reference to the 1982 film of the same name, where Vietnam veteran John Rambo (starred Sylvester Stallone) is also pursued by the authorities through the woods.
 * The typewriter Mick Davies uses to communicate is similar to concept of the Selectric 251, an inter-universe typewriter and communication device, from the television show Fringe.
 * Selectric 251 itself based from now out-of-manufacture IBM Selectric II, which produced in 1971.
 * The Boys spent wwo-months in a Maximum Security (Supermax) Facility in Colorado, in which ADX Florence is located, ADX Florence is a Supermax in which terrorists (Eric Rudolph, Zacarias Moussaoui, Theodore Kaczynski, etc), spys (Robert Hanssen, Harold Nicholson, etc), Cartel Leaders (Osiel Cardenas and Juan Garcia Obrego) and a FARC Leader (Simon Trinidad) are convicted and spent in a 23-hours day in solitary confinement, much like Dean and Sam are spent in this Episode.
 * Rick mentions Sam and Dean making it to the list of the FBI's Most Wanted in 2011. This is a reference to the two Leviathans who posed as Sam and Dean and committed several murders across different states. They appeared in "Slash Fiction".
 * He also mentions that Sam and Dean were presumed dead following a shoot out in Ankeny, Iowa.
 * Castiel has updated his voicemail: "This is my voice mail. Make your...voice...a mail."

Quotes
"Seat belt on. I drive fast."

- Mary to Castiel

"We're the guys who saved the world."

- Sam

"You know, this world, this sad, doomed little world, it needs you. It needs every last Winchester it can get, and I will not let you die. I won't let any of you die. And I won't let you sacrifice yourselves. You mean too much to me, to everything."

- Castiel to Winchester Family