User blog comment:Kajune/Supernatural spin-off, "Wayward Sisters" confirmed/@comment-1104107-20170621071741

I hope Donna is going to be in it too. She has to be.

However this will mean the show looses quite a few SPN female characters to a spin-off, but then I remembered it makes no difference since all of the wayward sisters possible characters only appears in 2 or 3 episodes a season. So they can still crossover on SPN as usual each season.