User blog comment:EmpyreanSmoke/Supernatural Q&A/@comment-213.152.161.20-20150924032331/@comment-24834479-20150924060451

1. Yes, they could. 2. They are physical beings, but they are also supernatural. Without teleportation, I would say they could be trapped within a black hole. 3. God isn't omnipotent in the show, so yes. 4. If he had a weapon that could kill him, then yes.