Special Children

Special Children refers to children to whom Azazel fed his blood when they were babies, having snuck into their homes after making a deal with their parents.

The result was that the blood awoke/created psychic abilities in them so they could (apparently) lead an army of demons in a war against humanity and God.

Around Season 2, Azazel wanted to test these children to find who would emerge victorious and also be the strongest, so he put them in an abandoned town called Cold Oak and told them only one could survive. This eventually triggered a fight among the special children. Azazel led everyone to believe that he wanted a leader for his demon army.

However, as it was later revealed, the endgame was bigger than just leading a demon army. Azazel chose the children because they were all potential vessels for Lucifer. The strongest one would be chosen to contain Lucifer throughout the apocalypse. Sam Winchester was the sole survivor and so, despite his greatest efforts, was taken over by Lucifer.

List of Special Children

 * Andrew Gallagher- (Deceased. Killed by a demon Ava Wilson summoned).
 * Ansem Weems- (Deceased. Shot by his twin brother, Andrew Gallagher).
 * Ava Wilson- (Deceased. Killed when Jake Talley broke her neck).
 * Jake Talley- (Deceased. Was shot dead by Sam Winchester).
 * Lily- (Deceased. Attempted to leave Cold Oak but was killed by an Acheri which Ava Wilson had summoned and controlled with her own powers).
 * Max Miller- (Deceased. Committed suicide by shooting himself in the head).
 * Rosie Holt- (Alive. A young baby girl who Azazel attempted to feed his blood to in the hope of making her another of his special children. Sam intervened, forcing Azazel to flee. Rosie is presumably still alive).
 * Sam Winchester- (Was killed by Jake but later brought back to life when Sam's older brother, Dean sold his soul to a Crossroads Demon. Sam later agreed to let Lucifer possess his body and was dragged into Hell alongside his half-brother Adam (who the Archangel Michael had taken over). Sam is currently alive, hunting demons with Dean (he returned from Hell).
 * Scott Carey- (Deceased. Died after being stabbed).

Trivia

 * The special children may be Nephilim as in John Winchester's Journal Azaezel is said to have fathered the Nephilim with human women.