User blog comment:ImperiexSeed/The oldest being, archangel or leviathan?/@comment-101.160.191.17-20120522085708/@comment-5110811-20120526213845

Yes, "when" means "during" Creation was being formed. But this still leaves a highly likely plausiblity that he was around before the Leviathans. Makes no difference at all if any. To be God's Scribe to take down dictation of everything at first hand basis knowledge directly from God - while he's doing his handiwork, it is highly likely he is older than everything created by God. Michael and Lucifer should be around as old as him.

War, famine, and pestilence represent human related concepts. The first "war" ever created was when Lucifer disobeyed God in bowing down to humans. Famine is hunger of any kind and pestilence is decay and disease. If you wipe out humanity, you call kill the three horsemen. Death is the only concept that is universal. Which God, being life -the Creator, is the opposite of.

I'd reckon the three horsemen have temporary immunity as long as humans are around. If humanity is wiped out, War, Famine, and Pestilence cease to have any meaning and they are then vulnerable to the Colt.

Remember, Lucifer said five things IN ALL Creation. Which means those five things are immune no matter what.