User blog comment:Corny4life/SEASON 12/@comment-87.110.1.150-20160311232716/@comment-1975828-20160312015813

The Darkness is amortal, said so in the first episode of season 11. Which means she cannot die, only kept locked up, so I doubt the universe would be affected.

As for season 12, I like to think all four archangels will return.

Making peace between family members only ever works with Sam and Dean, I think.